We Are Spark

Spark Therapeutics is a fully integrated, commercial company committed to discovering, developing and delivering gene therapies. Founded in 2013, Spark Therapeutics is the first company in the U.S. to receive FDA approval of a gene therapy for a genetic disease.

Today, as a member of the Roche Group, Spark is focused on breaking barriers for people and families affected by genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative disease, and currently has four programs in clinical trials. At Spark, we envision a world where no life is limited by a genetic disease.

A best place to work headquartered in Philadelphia, Spark is fueled by a diverse, experienced team united in a collective goal: challenging the inevitability of genetic diseases.


The bedrock of Spark’s culture is our company values. Our values celebrate championing the patient, breaking barriers in our work, demonstrating the respect you seek, owning your excellence, and committing to collaboration. Those values guide how we treat each other, how we partner in an equitable way with the communities we serve, and how we develop and deliver treatments for people living with genetic disease.

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