Senior Scientist, Medicinal Chemistry

La Jolla, California
November 24 2020
Full Time
Senior Scientist

We are seeking a highly motivated synthetic chemist who will contribute to the Oncology Medicinal Chemistry Department at Pfizer Worldwide R&D LaJolla, CA. As part of this group, the successful applicant will contribute through innovative synthetic chemistry tothedeliveryof clinical candidates aligned with the Oncology Research portfolio.


Role responsibilities include the ability to contribute to the development and enablement of a coherent synthesis strategy for oncology drug discovery. The candidate must understand the goals and strategies of the project and, as part of the synthesis team, positively and proactively influence the project team through the development of innovative and practical chemistry. The candidate will:
  • Develop and enable versatile and modular synthetic routes compatible with rapid new target synthesis, and will validate these routes through reduction to practice.
  • Build effective partnerships with other lines, in particular analytical, pharmaceutical sciences, and external research chemistry groups.
  • Develop scalable routes to preclinical drug candidates.
  • Liaise with outsourcing point of contact(s) to ensure provision of chemistry protocols and scientific guidance to external contract research chemists.
  • Publish and present research internally and externally to Pfizer.

  • Educational Qualifications:
  • Doctoral degree in synthetic organic chemistry.
  • Strong track record of achievement in synthesis of complex molecules with state of the art knowledge of modern synthetic methodologies and analytical and purification techniques.
  • Expertise in methodology development and successfully completed multistep syntheses.
  • Proven track record of creative thinking and consistent delivery as demonstrated by publication/presentation records.

  • Highly skilled synthetic chemist in the area of methodology development and multistep synthesis.
  • Strong knowledge of techniques related to purification and characterization of organic compounds.
  • Excellent written and oral communication skills; enthusiasm, integrity, self-motivation, strong interpersonal skills, ability to interact within a multidisciplinary team.
  • Comfortable working a highly innovative team environment.
  • Can effectively cope with change.
  • Responds well to scientific challenge and applies significant rigor to their own work.
  • Will scientifically challenge others in a constructive manner and demonstrate exceptional team working skills.

  • Previous experience in mentoring and development of junior scientists or students is a plus.


Other Job Details:
  • Eligible for Relocation Package
  • Eligible for Employee Referral Bonus

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Research and Development