Post Doctoral Fellow in Dystrophic and Genetic Cardiomyopathies

Post Doctoral Fellow in Dystrophic and Genetic Cardiomyopathies

UMN Job ID: 364480

The Kamdar lab at the University of Minnesota is  seeking a motivated and productive Postdoctoral Associate with expertise in gene editing and human induced pluripotent stem cells to join our dynamic research team. This position offers a unique opportunity to design and conduct  NIH-funded research experiments focused on dystrophic cardiomyopathy, utilizing iPSC-derived cardiac organoids for disease modeling and gene editing. Our goal is to advance the understanding of dystrophic cardiomyopathy and explore novel therapeutic strategies.

Research Focus

This role involves experimental work on dystrophic gene editing in iPSC-derived cardiac organoids to study muscular dystrophy and genetic cardiomyopathies. The candidate will apply CRISPR/Cas9 gene editing techniques (base and prime editing) to restore dystrophin and analyze cellular and molecular outcomes.

Key Responsibilities

• Design, execute, and analyze experiments investigating dystrophic cardiac disease models.
• Collaborate with laboratory colleagues and external scientific partners on experimental design and data interpretation.
• Maintain detailed documentation of experimental procedures, data analysis, and findings.
• Prepare and submit research manuscripts to peer-reviewed scientific journals.
• Present research findings at local, national, and international conferences.
• Provide mentorship and supervision for junior trainees in the laboratory.

Qualifications

Required:

• Ph.D. in biomedical sciences, molecular biology, stem cell biology, genomics, biomedical engineering, or a related field.
• Demonstrated experience in CRISPR/Cas9 gene editing in human stem cells.
• Strong track record of publishing in peer-reviewed journals and contributing to grant writing.

Preferred:

• Expertise in human iPSC techniques, including line derivation, cardiac differentiation, and gene editing.
• Excellent written and verbal communication skills.
• Preference will be given to applicants with demonstrated experience developing scientific protocols and scientific writing. Submit excellent letters of recommendation.

This position offers a highly collaborative and intellectually stimulating environment with opportunities for career development.

To apply, please submit a CV, cover letter, and contact information for three references to  kamd0001@umn.edu