Research Technician - LNP synthesis and/or flow cytometry

The Santangelo laboratory in the Wallace H. Coulter Department of Biomedical Engineering at Emory University, within the School of Medicine and Emory Vaccine Center is seeking several highly organized and detailed research technicians:

Research Technician: Flow cytometry

The Santangelo laboratory in the Wallace H. Coulter Department of Biomedical Engineering at Emory University, within the School of Medicine and Emory Vaccine Center is seeking a highly organized and detail-oriented research technician with a focus in flow cytometry. The ideal candidate will assist in panel design, perform cell staining, QC, and running the flow cytometer. The laboratory is outfitted with a state-of-the-art spectral flow cytometer with the ability to automatically run up to 96 samples. We are expanding the ability of the laboratory to analyze our novel RNA-based therapeutics. Emory University offers a highly collaborative work environment with strong research and career development opportunities.

Job Duties

• Must have familiarity with flow cytometry, cell sorting, preparation of single cell suspensions, and cell staining, etc.
• Must have experience with high-dimensional panel design (>15 colors).
• Must be able to learn to independently operate and QC the flow cytometer.
• Work with scientists to execute cell preps, cell staining, and analysis.

Minimum Qualifications:

• A bachelor's degree in a scientific field. 
• Seven years of professional research experience.

Preferred Qualifications:

• At least 5 years of experience with flow cytometry sample prep and instrument use.
• Prior experience with high-dimensional panel design required.
• At least 5 years of experience in a wet lab environment.

Research Technician: LNP formulation

The Santangelo laboratory in the Wallace H. Coulter Department of Biomedical Engineering at Emory University, within the School of Medicine and Emory Vaccine Center is seeking a highly organized and detail-oriented research technician to synthesize, test, and catalog lipid nanoparticles (LNPs). Using industry-standard formulation techniques, our lab encapsulates milligrams of high-quality synthetic mRNA to enable impactful therapeutic experiments (ACS Nano, Beyersdorf et al. 2022). The laboratory is outfitted with state-of-the-art testing equipment to produce and analyze formulated LNPs. We are expanding the ability of the laboratory to formulate multiple constructs simultaneously at higher scales, enabling advanced therapeutic experiments. Emory University offers a highly collaborative work environment with strong research and career development opportunities.

Job Duties:

• Formulates LNPs using industry standard techniques and equipment.
• Analyses LNPs for size, zeta potential, and encapsulation efficiency using DLS and RNA content methods.
• Works with scientists to further develop LNP formulation protocols.
• Prepares detailed quality summaries.
• Documents LNP production and testing details and reports to supervisor.
• Prepares shipments of reagents to both domestic and international partners.

Minimum Qualifications:

• A bachelor's degree in a scientific field. 
• Seven years of professional research experience.

Preferred Qualifications:

• Prior experience producing LNPs using industry-standard microfluidic based formulation devices.
• Prior experience performing DLS, zeta-potential, and RiboGreen RNA concentration techniques.
• At least 5 years of experience in a wet lab environment.

Interested applicants should email Daryll Vanover (daryll.vanover@emory.edu) and Loren Sasser (lsasser@emory.edu).

The COVID-19 vaccine or an approved exemption is currently only required for individuals working in a clinical setting. For more information on the University or Hospital policies, including exemptions, please see our website.

Emory University is dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, gender, genetic information, age, disability, sexual orientation, gender identity, gender expression, and veteran's status. Emory University does not discriminate in admissions, educational programs, or employment on the basis of any factor stated above or prohibited under applicable law. Students, faculty, and staff are assured of participation in University programs and in the use of facilities without such discrimination. Emory University complies with Executive Order 11246, as amended, Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veteran's Readjustment Assistance Act, and applicable executive orders, federal and state regulations regarding nondiscrimination, equal opportunity and affirmative action. Emory University is committed to achieving a diverse workforce through application of its affirmative action, equal opportunity and nondiscrimination policy in all aspects of employment including recruitment, hiring, promotions, transfers, discipline, terminations, wage and salary administration, benefits, and training. Inquiries regarding this policy should be directed to the Emory University Department of Equity and Inclusion, 201 Dowman Drive, Administration Building, Atlanta, GA 30322.

Emory University is committed to providing reasonable accommodations to qualified individuals with disabilities upon request. To request this document in an alternate format or to request a reasonable accommodation, please contact the Department of Accessibility Services at 404-727-9877 (V) | 404-712-2049 (TDD). Please note that one week advance notice is preferred.