Research Assistant II - Dr. Guarnerio's Lab (Genetics)
- Employer
- University of Texas MD Anderson Cancer Center
- Location
- Houston, Texas
- Salary
- Competitive
- Closing date
- Nov 8, 2024
View more categoriesView less categories
- Discipline
- Health Sciences
- Organization Type
- Healthcare/Hospital
You need to sign in or create an account to save a job.
Job Details
SUMMARY
At the Guarnerio lab , we're dedicated to unraveling the complex molecular mechanisms used by tumor cells to create a pro-tumorigenic tumor microenvironment (TME). We utilize cutting-edge technologies like single-cell RNA sequencing and spatial transcriptomics to study both mouse and human tissues. Our research is deeply rooted in translational science, with the goal of developing innovative cancer therapies that reprogram tumor cells and the TME.
Our recent publications include:
We are looking to recruit a Research Assistant II to help achieve our goals. The primary responsibility is to perform technical laboratory duties and carry out one of these exciting projects:
Ideal candidate will demonstrate technical proficiency in cell culture and possess a foundational understanding of molecular and cellular biology assays. Previous experience in mouse work and flow cytometry is preferred but not required. Strong communication skills and a team-oriented mindset are essential, along with the ability to manage and prioritize multiple tasks effectively.
KEY FUNCTIONS
EDUCATION
Required: Bachelor's degree with major course works in one of the basic sciences.
Preferred: Master's degree with major course works in one of the basic sciences.
EXPERIENCE
Required: One year experience in scientific or experimental research work. No experience required with preferred degree.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
At the Guarnerio lab , we're dedicated to unraveling the complex molecular mechanisms used by tumor cells to create a pro-tumorigenic tumor microenvironment (TME). We utilize cutting-edge technologies like single-cell RNA sequencing and spatial transcriptomics to study both mouse and human tissues. Our research is deeply rooted in translational science, with the goal of developing innovative cancer therapies that reprogram tumor cells and the TME.
Our recent publications include:
- Study of the MIF/CD74 axis in pro-tumorigenic macrophages (Tessaro et al., Cell Reports, 2022)
- Identification of anti-inflammatory, tumor-promoting circular RNAs (Piras et al., Nat Comm, 2022)
- Characterization of glyCAFs and T cell exclusion from the tumor mass (Broz et al., Nat Comm, 2024)
We are looking to recruit a Research Assistant II to help achieve our goals. The primary responsibility is to perform technical laboratory duties and carry out one of these exciting projects:
- Cancer-Associated Fibroblasts (CAF): Investigate their role in promoting tumor growth and immune exclusion.
- Circular RNAs: Explore novel mechanisms of immune exclusion and evasion.
- Sarcoma Stem/Progenitor Cells: Identify new tumor vulnerabilities and therapeutic targets.
Ideal candidate will demonstrate technical proficiency in cell culture and possess a foundational understanding of molecular and cellular biology assays. Previous experience in mouse work and flow cytometry is preferred but not required. Strong communication skills and a team-oriented mindset are essential, along with the ability to manage and prioritize multiple tasks effectively.
KEY FUNCTIONS
- Exercises considerable initiative and inventiveness in planning and executing the details of experiments.
- Execute experiments and critically analyze the results under the supervision of the PI or other lab members. Follow lab protocols and Standard Operating Procedures (SOPs). Process and evaluate data obtained in accordance with methods requested. Maintain accurate and detailed records of experimental data and protocols.
- Analyze, interpret, prepare and present data at lab meetings to contribute to scientific discussions.
- Assist in drafting study protocols and grant reports under the guidance of the PI.
- Learn new lab techniques and gain expertise in cancer biology.
- Performs regular monitoring of safety standards in the laboratory and maintains records of reagents and hazardous materials
- Organizes, inventories and orders laboratory supplies and performs other lab duties as assigned.
EDUCATION
Required: Bachelor's degree with major course works in one of the basic sciences.
Preferred: Master's degree with major course works in one of the basic sciences.
EXPERIENCE
Required: One year experience in scientific or experimental research work. No experience required with preferred degree.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
Company
The University of Texas MD Anderson Cancer Center in Houston is one of the world's most respected centers focused on cancer patient care, research, education and prevention. It was named the nation's No. 1 hospital for cancer care in U.S. News & World Report's 2023 rankings. It is one of the nation's original three comprehensive cancer centers designated by the National Cancer Institute.
You need to sign in or create an account to save a job.
Get job alerts
Create a job alert and receive personalized job recommendations straight to your inbox.
Create alert