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Senior Associate Scientist, Protein Solutions (Expression)

Employer
Pfizer
Location
Washington - Bothell, Washington
Salary
Competitive
Closing date
Nov 10, 2024
View more categoriesView less categories
Discipline
Health Sciences, Drug Development
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
Pharma
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

Position Summary

We are seeking a highly capable, enthusiastic and motivated research associate to assist in the expression of recombinant proteins using both molecular biology and mammalian tissue culture as part of the core protein expression and purification group. This person will play a critical role in supporting preclinical efforts in developing novel antibody-based therapeutics.

Principal Responsibilities
  • Expression of recombinant proteins, including antigens and antibodies via mammalian cell culture.
  • DNA preparation and vector assembly using standard molecular biology techniques.
  • Documentation and tracking of reagents and requests via ELN and LIMS system
  • Data analysis, report generation and presentation of results
  • Works with expression peers to fulfill protein reagent requests for Research
  • General lab support as necessary (eg. Buffer prep, Inventory resupply, ect.)


Required Qualifications
  • Bachelor of Science degree and 2-5 years lab experience in an academic and/or industry environment or equivalent
  • Protein production via transient transfection
  • Sterile technique for mammalian cell cultures
  • Experienced in balancing workload and changing priorities
  • Detail-oriented with strong analytical, organizational and written/oral communication skills
  • Ability to perform routine tasks independently, more advanced tasks under direction and complete work as part of a team


Preferred Qualifications
  • 2-5 years of protein expression experience
  • Transient transfection with Expi293 and/or ExpiCHO cells
  • Design and implementation of media optimization experiments
  • Protein expression using small volume plate based techniques
  • Experience using Hamilton or Tecan robotics platform
  • Protein quantitation using BLI or other methods
  • Tracking inventory and/or requests through computer systems
  • Basic knowledge of antibody structure and biochemistry


Additional Information:
  • Work Location Assignment:On Premise
  • Last Day to Apply: November 8, 2024


The annual base salary for this position ranges from $64,600.00 to $107,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development

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