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Senior Associate Scientist, Biofunctional Assays

Employer
Pfizer
Location
Pearl River, New York
Salary
Competitive
Closing date
Jun 5, 2024

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Discipline
Health Sciences, Drug Development
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
Pharma

Job Details

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a Senior Associate Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will have the important role to generate high-quality immunoassay data in a regulated Good Laboratory Practices (GLP) setting to support Pfizer's vaccine programs according to Standard Operating Procedures. You will support the technology transfer and integration of new laboratory immunoassays into the cGLP space, support assay validation projects and monitor immunoassay lifecycle. In addition, you will also support throughput activities and provide testing support for clinical and non-clinical research programs. Your skills and expertise will ensure that all work is to be done in a compliant manner according to relevant Standard Operating Procedure (SOP) guidelines and Good Lab Practices cGLP and/or (Current) Good Manufacturing Practices (part of GxP) cGMP guidelines.

Your significant experience of applying knowledge of principles, concepts, and practices of the discipline will make you a critical member of the team. You are proactive in contributing to all team discussions and creating an environment of collaboration.

It is your hard work and focus that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It

  • Contribute to achievement of immediate work group goals and collaborate with other team members.
  • Satisfactorily completes all cGLP (current Good Laboratory Practices) and safety training in conformance with requirements.
  • Perform sample preparation for preclinical and clinical serology in biofunctional assays to support vaccine development and clinical studies.
  • Complete required documentation for laboratory work involving bio-functional assays.
  • Execute qualifications/validations of new instruments and custom methods.
  • Organize assigned work according to established departmental priorities.
  • Collaborate with the Primary Pharmacology Group to ensure alignment around assay technology selection, assay quality criteria and validation requirements.
  • Interact with external vendors to obtain quotes, and purchase reagents for clinical testing where applicable.
  • Identify and report any experimental problems, proactively troubleshoot causative factors, and implement necessary corrections following discussion with supervisor.
  • Manage manual and robotic sample preparation, use and maintenance of appropriate equipment, and preparation of relevant reagents.
  • Train other analysts on established technologies and manage direct reports.


Qualifications

Must-Have

  • Bachelor's Degree
  • 3+ years of experience in cell culture and cell-based assays
  • Ability to use appropriate software to perform analysis of data
  • Basic laboratory skills in the area of aseptic technique, solution making, molecular biology, western blotting, biochemical assays and sample processing
  • Experience with experimental design and the interpretation of results
  • Effective verbal and written communication skills
  • Proficiency with personal computers, including word processing, Excel, PowerPoint and relevant scientific software


Nice-to-Have

  • Hands-on experience with microbial cell culture and enzymatic pathway analysis
  • Experience in developing and troubleshooting bioassays designed to assess antibody functionality
  • Experience programming in Excel VBA or R-Shiny
  • Drug discovery experience


PHYSICAL/MENTAL REQUIREMENTS

This position requires the typical physical demands of a general scientific laboratory environment during set up and operation of pharmaceutical laboratory equipment.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

This position may require occasional weekend work hours, as necessary. Individuals will be required to adhere to safe work practices including the proper use of personal protective equipment (PPE).

Work Location Assignment: On Premise

The annual base salary for this position ranges from $64,600.00 to $107,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development

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