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Senior Associate Scientist - Purification

Employer
Pfizer
Location
Pearl River, New York
Salary
Competitive
Closing date
Jun 8, 2024

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Discipline
Health Sciences, Drug Development
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
Pharma

Job Details

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

The Senior Associate Scientist is responsible for supporting mRNA production within the Vaccine Research and Development - Early Bioprocess Development group. The colleague will execute process activities required for the manufacture of DNA template, RNA drug substance, LNP drug product, and critical reagents. The responsibilities include UF/DF, affinity chromatography, column packing, and testing and analysis of in-process samples using various bioanalytical techniques. The colleague will be expected to summarize and evaluate study results. Detailed and accurate documentation of laboratory work and presentation of results is required.

How You Will Achieve It

  • Compliance with all Standard Operating Procedures (SOPs)
  • Complete all required trainings in compliance with departmental requirements and follow appropriate safety practices in the workplace
  • Plan, prioritize, and perform downstream processing of vaccine products and critical reagents
  • Perform in-process assays on vaccine products, process intermediates, and related experimental samples using biochemical/analytical tests
  • Collaborate with colleagues from partner groups in Vaccine Research and Development, including Bioprocess Fermentation, Analytical, and Formulation Development groups
  • Detailed, accurate, and timely documentation of experiments in a laboratory notebook


Qualifications

Must-Have

  • BS degree in biology, chemistry, biochemistry, chemical engineering, or related field with 2-5 years relevant experience, or a MS degree with 0+ years relevant experience.
  • Prior experience with bioprocessing/purification
  • Experience running chromatography with AKTA systems using UNICORN software
  • Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is desirable
  • Strong verbal and written communication skills with attention to detail
  • Self-motivated and a positive attitude
  • Ability to learn new techniques, follow instructions, keep accurate records, and comply with SOPs
  • Proven ability to work independently in hands-on laboratory setting and collaborate as part of a team


Nice-to-Have

  • Knowledge and ability to independently execute purification/recovery activities
  • Proficiency in various techniques such as FPLC/HPLC, UV-Vis, and SDS-PAGE to isolate and/or characterize biomolecules


PHYSICAL/MENTAL REQUIREMENTS

Standard laboratory conditions - sitting & standing for periods of time

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

40 hours per week

Work Location Assignment: On Premise

The annual base salary for this position ranges from $64,600.00 to $107,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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