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Vice President, Late Stage Clinical Development - Breast Oncology TA Development Head

La Jolla, California, United States;United States - Washington - Bothell
Closing date
May 10, 2024

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Life Sciences, Oncology
Position Type
Full Time
Job Type
Academic Dean/Dept. Head, President/CEO/Director/VP
Organization Type

Job Details


Pfizer Oncology has an industry-leading portfolio of 25 approved innovative cancer medicines, including major therapies for metastatic breast cancer, prostate cancer, urothelial carcinoma, and haemato-oncological malignancies. Pfizer's in-line portfolio is focused on four broad, key areas: breast cancer, genitourinary cancer, hematology, and precision medicine, complemented by an extensive pipeline of over 50 programs in clinical development.

The Oncology Late-Stage Breast Cancer Therapeutic Area (TA) Head will report to the Chief Development Officer for Oncology and oversee the development and execution of comprehensive late-stage clinical development strategies for Pfizer-oncology assets in Breast Cancer. This role will collaborate cross-functionally across Pfizer Oncology to define and oversee execution of integrated development strategies. The Late-Stage Breast Cancer TA Head will build, engage, and retain a team of drug development experts with deep expertise in oncology.

The position has direct impact on the Pfizer Oncology portfolio and requires an exceptional leader in oncology drug development with a thorough understanding of end-to-end development, therapeutic area expertise, an understanding of related products, the external landscape, and the executive leadership capabilities needed to realize the potential of the portfolio and deliver medicines to patients. This is a highly visible, critical position which requires strategic thinking, leadership and exceptional communication skills with the ability to work with external partners and potential business development partners. May participate in and lead business development efforts as assigned.


Major responsibilities include but are not limited to:
  • Provide executive leadership of late-stage development programs for designated therapeutic area across Pfizer Oncology governance committees, as well as clinical development partnerships and collaborations.
  • As the senior drug development expert for their assigned therapeutic area, the incumbent will drive innovative drug development strategies and plans in their portfolio by leveraging deep expertise and insights from key stakeholders and team members.
  • Apply oncology drug development and disease-area knowledge to ensure that the programs are managed in an efficient and rigorous manner as reflected in the design, conduct, and prioritization of initial and lifecycle indications with a high likelihood of clinical, regulatory, and commercial success.
  • Ensure continuity in development plans and identify gaps to be addressed through clinical development. Enable effective decision making based upon objective clinical safety and efficacy response measures.
  • Actively monitor progress of all studies and maintain alignment to strategic objectives for therapeutic area and broader oncology portfolio. Proactively identify and mitigate potential risks, escalating for awareness as appropriate.
  • Lead a team of Global Development Leads and Medical Directors to deliver excellence and quality throughout all phases of the late-stage development process.
  • Effectively align resources (direct & indirect) to facilitate lightspeed development of high-quality, cost-effective programs in alignment with clinical development and commercial priorities for Pfizer Oncology.


  • MD, MD/PhD or equivalent with extensive clinical experience.

  • 10+ years of oncology development experience within the Biotech or Pharmaceuticals industry
  • Extensive experience and strong understanding of biopharmaceutical drug development, the competitive landscape / oncology market dynamics / evolving treatment landscape and HCP and patient insights, bringing deep clinical and external stakeholder insights to decision making from pre-POC to post-POC and commercialization.
  • Direct experience in preparation of regulatory submissions as a functional or matrix leader (preferred). Candidates with outstanding individual contributions to one or more regulatory submissions will also be considered. Track record of Health Authority interactions and committee presentations (e.g., ODAC) preferred.
  • Direct experience managing and leading marketing authorization applications in the US, EU and globally.
  • Clinical and/or drug development in breast cancer preferred.
  • Experience in other function areas (e.g., medical affairs or drug safety) preferred
  • Experienced leader who can work collaboratively across a complex cross functional team of stakeholders. Must be able to lead with a lightspeed, innovative, and entrepreneurial mindset.
  • Understanding of related disciplines (e.g. biostatistics, regulatory, pre-clinical pharmacology, pharmaceutical sciences).
  • Demonstrated scientific productivity (publications, abstracts, etc.).
  • A thorough understanding of Oncology and cancer biology and its relationship to drug development.
  • Experience in functioning effectively as a member of a matrixed/multidisciplinary team.
  • Insight into and understanding of principles related to evaluating business deal structures including commercial collaborations, acquisitions, and divestitures.
  • Experience in budgetary management and decision making.

  • Proven expertise in fostering employee development and well-being through effective people development, and motivational team leadership.
  • A strong ability to influence all levels of the organization, including both senior-level colleagues and leaders across the company.
  • Must have executive leadership skills; able to lead and motivate a team of experienced professionals and experts that have deep knowledge in oncology and are leaders within Oncology Late-Stage Development and the broader Oncology division.
  • Ability to build and maintain productive working relationships with key opinion leaders in therapeutic area.
  • Exceptional verbal and written communication and presentation skills.

The annual base salary for this position ranges from $299,600.00 to $499,400.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 30.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | ( Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.



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