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Scientist - In Vivo Pharmacology

La Jolla, California
Closing date
Apr 27, 2024

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You will participate in pre-clinical drug discovery and development projects with a focus on Cancer Immunology. You will work as a key member of an in vivo team, perform a range of in vivo studies that generate critical project data for project teams. You will be a technical and scientific specialist in the conduct of oncology in vivo studies and will be responsible for study planning, scheduling and execution including, sample preparation and collection, appropriate documentation; and accurate exporting, formatting, and presenting data for multidisciplinary project teams. You will work collaboratively with all in vivo team members and project teams to understand their needs, obtain the necessary approvals and deliver in a timely and efficient manner.

  • Plan, execute and analyze in vivo pharmacology studies
  • Characterize new in vivo mouse models, including syngeneic tumor and genetically engineered mouse (GEM) models, to study biologic mechanisms and support exploration of novel therapies.
  • Conduct in vivo studies to evaluate and establish efficacy, PK/PD relationship, combination strategy, biomarker identification and analysis.
  • Perform ancillary in vitro and ex vivo assays to characterize effects of experimental medicines that may include FACS, scRNAseq or other assays as needed.
  • Document and interpret experimental results
  • Present results within a multidisciplinary team environment.
  • Ensure appropriate use of animals in compliance with all regulatory requirements and internal standards.


  • Bachelor's degree with 6+ years relevant experience or equivalent.
  • Experience with animal models of human cancers.
  • Hands on in vivo skills (IV, PO dosing), blood/tissue collection.
  • Ability to follow novel scientific or technological developments, and to implement them in the laboratory.
  • Excellent written and oral communication and presentation skills
  • Proficiency with all common office and scientific software
  • Ability to multi-task and work productively in a fast-paced, highly collaborative, and diverse team environment.

  • Work experience in an industry setting highly desired

  • Must be willing and able to work after hours as needed to ensure study integrity

Additional Information:
  • Work Location Assignment:On Premise
  • Eligible for Employee Referral
  • Last Day to Apply: April 25, 2024

The annual base salary for this position ranges from $74,900.00 to $124,800.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | ( Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development

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