Senior Research Assistant - Systems Biology (Spatial Transcriptomics)

Systems Biology is an interdisciplinary department that is pushing the boundaries of cancer research by integrating technology development, bioengineering, data science, and systems biology. We leverage our massive clinical resources and unmatched access to patient tissue samples to study some of the biggest questions in the cancer field, on topics that include premalignant progression, metastatic dissemination, and therapeutic resistance. Our faculty members represent top-notch scientists working in a wide range of areas of cancer research and commonly use multi-omic approaches to understand the interaction of genotypes and phenotypes at single cell and spatial resolution.

SYSTEMS BIOLOGY

KEY FUNCTIONS

• Perform spatial genomics experiments.
• Perform single cell sequencing experiments.
• Maintains clear and systematic records for benchmarking assays and equipment.
• Generates new clear SOP for core before release of protocols.
• Trains others on new protocols.
• Assists core service.
• PCR, qPCR, DNA, RNA isolation and Quality Control.
• Tissue sectioning and tissue staining (H&E).
• Isolates single cells for genomic analysis.
• Prepares libraries for single cell sequencing and next-generation sequencing libraries.
• Prepares slides for spatial transcriptomics assays.
• Interfaces with core service team and data analysis team about new protocols, experimental issues, and sample quality control requirements
• Assists with the maintenance of laboratory equipment and the overall organization of the core
• Constructs, assembles and operates laboratory apparatus and equipment.
• Assists with administrative responsibilities associated with core duties such as maintain records of core samples, data received, data produce and their locations.

Education

Required: Bachelor's degree in one of the natural sciences or related field.

Preferred: Master's degree in one of the natural sciences or related field.

Experience

Required: Three years of experience in scientific or experimental research work. With preferred degree, one year of required experience.

Preferred: Human tissue processing, next generation sequencing, spatial transcriptomics assays and/or benchmarking genomics assays.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html