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Scientist

Employer
Pfizer
Location
Andover, Massachusetts
Salary
Competitive
Closing date
Feb 28, 2024

View more

Discipline
Health Sciences, Drug Development
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
Pharma
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.

What You Will Achieve

Deliver results in a fast-paced matrix-oriented setting, be a contributor to key process purification steps and hold responsibility for various downstream process development activities. This advertised role is in support of products and process development for biotherapeutics and vaccines, including antibodies, antibody-drug conjugates, therapeutic proteins, and polysaccharides in commercial operations and late-stage clinical development. The candidate will work across downstream purification functions, projects, and global sites.

How You Will Achieve It

  • The MSAT (Manufacturing Sciences and Technology) Downstream group provides technical expertise in downstream process development, including purification/characterization/optimization activities, various support for upstream projects that require downstream skills, and support for routine product manufacturing operations.
  • Candidate should have in-depth scientific knowledge and experience in a wide array of techniques such as Depth Filtration, Ultrafiltration, a variety of Chromatography separations, and ideally familiar with standard equipment, e.g., AKTA, Repligen KrosFlo, Sartorius Advanced, SoloVPE
  • Leveraging experience to develop and update current purification processes.
  • Ensure the proper and timely execution of purification processing to support wider team.
  • Perform scale-down purification processes development and support tech transfer activities.
  • Qualified candidates will serve as purification and biochemistry experts within the department and project teams, while proactively building on existing product knowledge and experience.


QUALIFICATIONS

Must Have
  • Applicant must have a High School Diploma (or Equivalent) and 8 years of relevant experience OR an associates degree with 6 years of experience OR a bachelors with at least 3 years of experience OR Masters with more than 1 year of experience.
  • Demonstrated technical writing skills and effective communication are strongly desired.
  • Experience with technologies (AKTA, UF/DF, Depth Filtration, Chromatography) focused on protein purification (e.g., monoclonal antibodies), enzymatic reactions, and other novel modalities.
  • Ability to utilize common software and computer systems (Outlook, Teams, Unicorn, Excel)


Nice to Have
  • B.A./B.S with 8+ years; MS with 5+ years; Ph.D. with 2+ years of experience with interdisciplinary process development teams, industrial experience developing purification strategies or methods in support of product and process development in the field of biotherapeutics.
  • Knowledge and experience in Critical Quality Attributes (CQA) principles practices, product specifications and specification setting.
  • Demonstrated technical skills and scientific expertise in purification process development and troubleshooting.
  • Familiarity with mRNA lipid nano particle formulation and Final Drug Product (FDP) processes.
  • Change agile, functional in a fast-paced team environment where multi-tasking required.
  • Enthusiastic about communicating to a broad range of stakeholders (from novices to experts) and seeking agreement in complex situations.
  • Curiosity about seeking and applying current relevant scientific literature.


PHYSICAL/MENTAL REQUIREMENTS

Normal lifting, sitting, standing and walking requirements to facilitate support of staff in the office and on the floor (laboratory, suites, etc.).

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Position is first shift Monday through Friday. Some off hour (night/weekend/holiday) support may be required to support staff and operations.

Work Location Assignment:On Premise

OTHER JOB DETAILS
  • Last Date to Apply for Job: February 14, 2024
  • Referral Bonus Eligibility: YES
  • Eligible for Relocation Package: NO


The annual base salary for this position ranges from $78,000.00 to $130,000.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 10.0% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development

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