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Postdoctoral Fellow - Diabetes Complications and Metabolism

City of Hope
Duarte, CA
$34.00 - $37.55 / hour
Closing date
Feb 27, 2024

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Life Sciences
Position Type
Full Time
Organization Type

Job Details

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope , where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The Department of Diabetes Complications and Metabolism is at the leading edge of research on the complications of diabetes and was the first to study epigenetic changes in diabetes complications. The department uses state-of-the-art computational and systems biology data-analysis methods, genomic and epigenomic profiling approaches, novel transgenic mouse models, and translational approaches to study connections between diabetes, obesity, and cancer.

A postdoctoral position is immediately available in the Tompkins lab within the Department of Diabetes Complications and Metabolism at City of Hope. We are seeking highly motivated individuals interested in stem cell biology (pluripotent and hematopoietic), directed differentiation, and locus-specific epigenetic editing in regenerative medicine. For more information about the Tompkins lab, please visit here .

City of Hope offers an outstanding training environment for postdoctoral scientists. For more information, please visit here.

As a successful candidate, you will:
  • Explore the therapeutic potential of basic discoveries in epigenetic control of cell fate and epigenetic memory in diabetes complications.
  • Evaluate both site-specific epigenetic correction and innovative systemic approaches to correcting epigenetic events in diabetes complications.
  • Be involved in several interconnected projects.
  • Conduct organized, high quality, and reproducible research.
  • Routinely meet with PI, core team, and collaborators to accelerate research findings.
  • Present your findings at select conferences and departmental seminars.
  • Seek out extramural funding for an individual fellowship.

Your qualifications should include:
  • Ph.D. in molecular biology, epigenomics, regenerative medicine, or related discipline within the last 5 years.
  • Productive research history, including published first author publication(s) in quality biomedical research journals.
  • Strong public speaking ability to publicly share your research findings in departmental and national conference settings.
  • Excellent interpersonal communication skills and ability to work alongside a diverse group of productive scientists.
  • Experience in pluripotent stem cell culture and directed differentiation.
  • Experience in conventional gene editing systems such as CRISPR/Cas9.

Preferred qualifications:
  • Experience in analyzing omics data sets.
  • Handling and isolating primary stem cell cultures, standard molecular biology assays, and integrative omics.
  • Prior mouse handling experience, including histological assessments of vasculature, liver, and/or islet cell biology.
  • Routine data sets for analysis will include Infinium DNA methylation arrays, and high throughput sequencing data.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here .


City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research.  City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

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