Research Associate II - Cancer Cell Lines and Mouse Models

City of Hope
Duarte, CA
Closing date
Mar 2, 2024

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Life Sciences, Cell Biology, Cancer Research
Position Type
Full Time
Organization Type

Job Details

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

Under the supervision of Dr. Heather McGee, the Research Associate II will contribute to research projects focused on studying the immune response to radiation. Dr. McGee's research is currently supported by an NIH R00 grant from the National Cancer Institute, the AACR-Debbie's Dream Award for Gastric Cancer Research, the City of Hope Chancellor's Award and a start-up package from City of Hope. Research findings from Dr. McGee and colleagues have been published in Nature, Nature Communications, Clinical Cancer Research, Journal of Immunology, Journal for Immunotherapy of Cancer, International Journal of Radiation Oncology* Biology* and Physics, and numerous other journals.

As a successful candidate, you will:

· Serve as lab manager, responsible for ordering supplies/maintaining inventories of supplies, updating the lab's IACUC, IBC and other protocols, and genotyping mice/ maintaining the lab's mouse colony.

· Assist other scientists in the lab with a variety of research experiments, including culturing and irradiating tumor cell lines, performing molecular biology assays, performing in vivo murine experiments, harvesting murine tumors and isolating immune cells, and using FACS to characterize immune cell populations.

· Be responsible for analyzing data using Flow Jo, ImageJ and Prism software, as well as compiling results and preparing presentations for lab meetings.

· Utilize established protocols to perform a variety of in vitro experiments (in cancer cell lines) and in vivo experiments (in murine tumor models) under the guidance of senior scientists in the lab.

· Update IACUC, IBC and IRB protocols for the lab.

· Update laboratory experimental protocols for the lab.

· Genotype mice and help maintain the lab's mouse colonies.

· Bachelor's degree. Masters degree preferred

· 2+ years of related research/laboratory experience with a Bachelor's degree or 1+ year related research/laboratory experience with a Master's degree.

· Experience with flow cytometry and tumor immunology is preferred.

· Experience with cell culture and murine tumor models is preferred.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here


City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research.  City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

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