Post-Doctoral Research Associate Senior
Staff Scientist (Lu Laboratory)
Department of Cellular and Molecular Biology, University of Texas at Tyler School of Medicine, University of Texas at Tyler Health Science Center
We are seeking one highly self-motivated scientist to join an exciting, interactive, and productive research team and work on interdisciplinary projects in human viral pathogens, including HIV-1, SARS-CoV-2, RSV, etc. The ideal candidate should have relevant extensive research experience in virology, molecular biology, biochemistry, or biophysics. Salary ranges from $60,000/year (plus fringe benefits) commensurate with experience. Our campus is in Tyler, East Texas, with a low cost of living. Tyler is known for the rose capital of America, towering pine trees, medicare facilities, and choice of retirement places. The PI Lu and the growing lab have a strong research record in understanding function-determining structural dynamics of HIV-1 and SARS-CoV-2 surface spikes (Nature, 2019, 568: 415-419; Cell Host & Microbe, 2020, 28: 880-891. e8; Nat Struct Mol Biol, 2020, 27: 726-734; J Virol. 2020, 94(17): JVI.00597-20; mBio, 2022, 13 (1), e03227-21; Cell Chem Biology, 2023, accepted (BioRxiv [preprint], 2023, PMC10002649)). More details can be found at https://www.ncbi.nlm.nih.gov/myncbi/maolin.lu.1/bibliography/public/.
The Lu laboratory investigates virus-host interactions using multiple cutting-edge technologies involving biophysical imaging tools, genetic code expansion, click chemistry, virological techniques (infectivity, fusion, titration, antigen-antibody binding, etc.), molecular biology (cloning, cell culture, protein purification, flow cytometry, etc.), cryoEM/cryoET, and MD simulations. We aim to combine different ideas and expertise to understand the critical role of conformational/structural presentations and dynamics of spike proteins of enveloped viruses in cell entry and immune evasion. Research projects in the Lu lab are well-funded by NIH (MIRA R35, R56, and upcoming R01) and foundations (Gilead and amfAR). We have built a broad collaborative network involving multiple prestigious research groups worldwide. We are affiliated with Duke University Center for HIV Structural Biology, with numerous resources and opportunities to facilitate the career development of trainees in structural biology.
Ideal candidates should hold a Ph.D. or equivalent degree, communicate well in English, have a great publication record, and have two or more areas of the following training experience.
1) Virology: Lentiviruses, coronaviruses, or other human viral pathogens.
2) Biomedical imaging, such as live cell imaging, super-resolution, single particle tracking, confocal, TIRF, etc. Programming experience is highly preferred.
3) Biochemistry/Structural biology: protein purification, crystallography, cryoEM/ET, SPR, ELISA, etc.
4) Molecular biology: molecular cloning, western blots, flow cytometry, qPCR, etc.
Self-motivated, quick-learner, energetic applicants are highly encouraged to apply.
Please email a cover letter explaining relevant work experience and potential starting date, a CV, and the names and contact information of three references to Dr. Maolin Lu, email: email@example.com or firstname.lastname@example.org
As an Equal Opportunity Employer, the University will, in accordance with State and Federal law and regulations, provide equal opportunity in all employment related activities without regard to race, color, religion, national origin, gender, age, disability, sexual preference, or status as a disabled veteran or a veteran of the Vietnam Era. The University requires pre-employment drug & alcohol screening, proof of COVID-19 vaccination and/or medical or religious exemption, and health immunizations and criminal background check on all hires. Specific job requirements or physical location of some positions allocated to this classification, may render this position security sensitive, and thereby subject to the provisions of Section 51.215, Texas Education Code