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Postdoctoral Fellow - Structural Biology

City of Hope
Duarte, CA
$31.00 - $34.23 / hour
Closing date
Jan 27, 2024

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Life Sciences, Structural Biology
Position Type
Full Time
Organization Type

Job Details

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope , where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The laboratories of Dr. Jeff Perry, a Structural Biologist, and Dr. Javier Gordon Ogembo, a Vaccinologist, are currently seeking a highly motivated and talented individual to fill a postdoctoral position in the field of gamma-herpesvirus structural biology. The goal of the postdoctoral candidate will be to elucidate the mechanisms of gamma-herpesvirus entry and contribute to vaccine development. If you are looking for a challenging and exciting opportunity to advance your research career in oncogenic gamma-herpesviruses and cancer, we invite you to join our multi-disciplinary lab. For more information about Dr. Ogembo's lab, please visit here.

As a successful candidate, you will:
  • Access state-of-the-art facilities and resources for transitional science in a vibrant, collaborative research community.
  • Utilize FDA-approved facilities for producing investigational drugs and biologics for clinical trials.
  • Work in facilities designed to meet rigorous regulatory standards, ensuring safety and efficacy of developed products.
  • Seize the opportunity as a postdoctoral fellow to collaborate with leading experts, contributing to cutting-edge research in viral entry, oncovirology, and vaccinology.
  • Explore interactions between viruses and host cells, advancing understanding in these crucial areas.
  • Experience an exciting research environment, enhancing your career while contributing to impactful projects.

Your qualifications should include:
  • A Ph.D., Ph.D/DVM, or Ph.D/MD degree(s) in a related field and a strong background in protein biochemistry and structural biology.
  • Cell culture and aseptic technique: culture, handling, and maintenance of bacterial and mammalian cells (multiple cell lines), cryopreservation.
  • Protein production and structural assays: protein expression in different cell systems and purification; protein crystallography and/or cryo-electron microscopy; circular dichroism (CD) spectroscopy, mass spectrometry, isothermal calorimetry and/or surface plasmon resonance.
  • Immuno-assays: western blot, ELISA, flow cytometry, immunofluorescence assay, immuno-histochemistry.
  • Molecular cloning and basic DNA/RNA assays: molecular cloning, DNA/RNA isolation from cells, conventional PCR.

Preferred qualifications:
  • Experience in virology, cancer vaccines, T-cell immunology, and/or the use of animal models will be considered as a plus.
  • Virology assays: virus production and titration, virus neutralization, plaque assays.
  • Advanced DNA/RNA assays: DNA isolation from tissue, qPCR, RT-qPCR.
  • Pre-clinical animal models: animal handling (mice and/or rats), immunization, blood collection, tissue processing.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here .



City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research.  City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

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