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Senior Research Assistant - Immunoprofiling

University of Texas MD Anderson Cancer Center
Houston, Texas
Closing date
Oct 18, 2023

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Health Sciences
Organization Type

Job Details

The mission of The University of Texas M. D. Anderson Cancer Center is to eliminate cancer in Texas, the nation, and the world through outstanding programs that integrate patient care, research and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees and the public.


The translational molecular pathology -immunoprofiling platform (TMP-IL) translates immunopofiling data into research that is clinically applicable and can aid in the treatment and outcome of future cancer patients. The primary purpose of the Sr. Research Assistant position is to assist in the preparation of tissue and fluid specimens for research experiments. The scope of the position is to aid in and carry out laboratory research projects involving assessment of the immune system using flow cytometry, cellular assays and identification of circulating biomarkers. Technical experience working with cell lines is desirable. The Sr RA must be able to provide technical and coordination skills in carrying out various research projects, coordinates procedures, and performs technical laboratory duties in accordance with general and/or specific plans. Excellent attention to detail and detailed record keeping is required.


Technical Functions

Function in an independent manner, and have the ability to design research experiments.
Discusses goals of each project with supervisor; with the help of supervisor, develops a step-by-step written procedure outlining the specific actions required to conduct the experiment before proceeding
Ability to work on several research projects concurrently in an independent manner
Perform flow cytometry and proteomic detection assays such as Luminex and MSD.
Engage in performing ELISPOTs and testing procedures for generation of single cell suspensions from tumor tissue.
Compile research data and submit results to for inclusion in publications, grants or protocols.

Expansion of tumor-infiltrating lymphocytes and primary tumor cells lines from solid tumors.

Perform TIL expansion setup, tumor line setup and expansion under sterile conditions.

Laboratory Operation

Carry out lab duties that may include organization, EHS compliance and lab safety.
Responsible for major participation in the development of Standard Operating Procedures (SOPs) for new platforms and assays
Monitors and maintains supply inventory so that work flow is not negatively affected.

Collaboration and Presentation

Interacts and participates in collaborative studies inside and outside MD Anderson.
Trains other research personnel on established assays, and use of laboratory equipment.
Prepare final reports in the format requested for the data generated by suggested due date.
Willingness to learn and to help others in the implementation of new techniques.

Data Maintenance

Enter and maintain data from research activities in notebook/computer databases as appropriate.
Performs and documents all required quality control/quality assurance.
Maintains accurate, detailed records and experimental data and protocols
Prepares graphs, slides and tables via photography, computer, or manually.
Collaborates or assists supervisor and senior research staff with preparation of reports and grant requests.
Acquires and maintains proficiency in computer functions.
Able to work with database, graphing and word processing computer programs such as Microsoft Excel, Power Point, Word and Prism.
Must be able to fully communicate results and understand instructions from principal investigator and colleagues.

Other duties as assigned

Bachelor's degree in one of the natural sciences or related field. Three years of experience in scientific or experimental research work. With preferred degree, one year of required experience It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.


The University of Texas MD Anderson Cancer Center in Houston is one of the world's most respected centers focused on cancer patient care, research, education and prevention. It was named the nation's No. 1 hospital for cancer care in U.S. News & World Report's 2023 rankings. It is one of the nation's original three comprehensive cancer centers designated by the National Cancer Institute.

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