The Leroy T. Canoles Jr. Cancer Research Center at Eastern Virginia Medical School is in search of a candidate to fulfill the duties of a Research Scholar/Postdoctoral Fellow in the Center for Biomedical Proteomics. The research team is a leader in the field of biological mass spectrometry, proteomics and cancer biomarker discovery and development. We have continuing long-term translational research funding to develop biomarkers for prostate cancer disease stratification. As a Biomarker Characterization Center (BCC) of the NIH/NCI Early Detection Research Network (EDRN), our broad objective is to identify and validate novel post-digital rectal exam urine and tissue biomarkers for early detection of aggressive forms of prostate cancer. In our collaborative BCC we continue to participate in intensive, long-term and large-scale development of clinically robust mass spectrometry based multiomics assays that incorporate these novel biomarkers for validation and quantitation of clinical performance. The successful candidate will be incorporated into the project team and will participate in project planning, experimental design, sample processing, LC/MS, computational and pathway analysis, data interpretation. The position will provide an excellent opportunity to learn and utilize quantitative proteomics as well as cell and molecular biology, while working with dynamic and interdisciplinary research teams at the Eastern Virginia Medical School. The position will also include opportunities to co-author publications and to contribute to the development of grant proposals. The successful applicants will join a team working closely with research scientists, graduate students, and faculty from other research groups. Professional development is strongly encouraged including support for professional travel to relevant conferences.
The successful candidates should have a PhD degree in biochemistry, chemistry, proteomics, or related fields, and demonstrated working experience with mass spectrometry-based proteomics using LC-MS/MS, HPLC, PRM, with instruments from Thermo Fisher Scientific (Eclipse, Fusion Lumos and Q-Exactive) and Sciex (Q-TRAP 4000). Experience in MS sample preparation strategies, MS method development and MS data analysis platforms (Mascot, Skyline, MaxQuant, Proteome Discoverer, Compound Discoverer, Byos, FragPipe, etc) is necessary and experience in metabolomics/Lipidomics/small molecule analysis and in the integration of large ‘omic datasets will be a plus.
Excellent written, verbal, and interpersonal communication skills. Demonstrate attention to detail, strong organizational skills, and innovative approach to experimental design. Computer literate and working knowledge of common software applications (word processing, spreadsheet, and database). Analytical ability sufficient for data analysis; mathematical ability sufficient to perform algebraic calculations and statistical analysis. Expressed willingness to teach others and share results. Capable of meeting time demands necessary to execute and complete experiments.
Interested applicants can apply online at http://www.evms.edu under Career Opportunities. The title for this staff position is Research Scholar for the Cancer Research Center and the position number is to be determined (TBD).
QUALITY OF LIFE:
Located in the city of Norfolk, EVMS serves the southeastern region of Virginia known as Hampton Roads. The area is rich in history, culture and education. It also provides easy access to the Outer Banks, Virginia Mountains, and the state capitol in Richmond and to Washington D.C. Norfolk/Virginia Beach was Rated Almanac’s #1 metropolitan area, places for recreation. Live and work in an environment abundant in history, culture, and recreation.
EVMS is EOE/including disability and veterans and Drug and Tobacco Free workplace.