The Center for Clinical Cancer Genetics & Global Health, Section of Hematology/ Oncology, and Department of Medicine at the University of Chicago is seeking a highly motivated postdoctoral fellow (including recent graduates) to study breast cancer biology in diverse populations. The lab focuses on the roles of tumor suppressor genes, pseudogenes, and long non-coding RNAs in various signaling pathways involved in tumor initiation, progression, and metastasis. These projects will utilize a combination of patient-derived organoids and mouse models, and cutting-edge technologies such as CRISPR and multi-omics approaches. Current areas of research focus in the lab include RNA-induced innate immune responses, tumor-microenvironment interactions, molecular mechanisms of treatment resistance as well as computational biology, whole genome sequencing, and comparative analyses of breast cancer across the African Diaspora.
Trainees will benefit from a highly collaborative research environment with multiple state-of-the-art core facilities and opportunities for cross/multi-disciplinary collaboration. Successful trainees will lead multidisciplinary research projects under the guidance of a faculty mentor (or mentorship team). Candidates will be expected to pursue an academic research career by developing their own line of research, undertaking data analysis, generating peer-reviewed manuscripts, and developing grant proposals that will support these research initiatives.
Candidates should possess a PhD, MD or equivalent in molecular and cellular biology,
biochemistry, molecular pharmacology, cancer immunology, computational biology, human genetics or a related field. Candidates with high proficiency in humanized or xenograft cancer models are highly encouraged to apply. Experience in tumor organoid establishment and drug screening/testing in preclinical models is desirable. Candidates should be eligible to work in the USA, able to work independently and as part of a team in a highly collaborative research environment.
The Department of Medicine at the University of Chicago provides a stimulating and interactive environment with several laboratories interested in diverse aspects of human variation, statistical and computational genetics, cancer genetics and clinical pharmacology. Interested candidates should submit an electronic copy of their curriculum vitae, a one-page letter describing their prior research experience, current interests and goals, and should provide names and contact information of three references to: Lise Sveen email@example.com.
The University of Chicago is an Affirmative Action/Equal Opportunity Employer