Senior Scientist - Protein Purification, Early Bioprocess Development (EBPD), Vaccine R&D

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a Senior Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. Your strong foundation in general scientific practice, its principles and concepts will help in meeting critical deadlines. You will be relied on as a technical contributor to assess the assigned tasks and make decisions that involve direct application of your knowledge.You will perform diverse protein purification operations required to generate protein subunits vaccine candidates, optimize purification procedures using a broad range of purification techniques. You will also perform analysis / characterization of isolated macromolecules with various bioanalytical methodologies. You will be recognized as a technical expert and a scientific contributor. With your deep knowledge of the discipline, you will be an active team member whose decisions impact the project. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience. You will be forecasting and planning resource requirements for your project team. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide team members as needed. It is your hard work and dedication that will make Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It

• Regularly contribute and influence at the project team level.
  
• Engage and work with external collaborations and Contract Research Organizations (CROs).
  
• Apply technical skills to complete assigned work within own work group/project team.
  
• Develop, optimize, and scale-up protein purification processes for selected targets. Characterize purified proteins using variety of analytical techniques.
  
• Assist in developing new assays and adapt existing assays to new materials.
  
• Discuss analytical issues with team members to help advance objectives.
  
• Present problems and propose solutions in discussion with group members. Offer insights based on experience to group members to help solve problems.
  
• Collaborate with colleagues towards introduction of new technologies to improve and accelerate downstream process development and improve process efficiency.
  
• Maintain an organized laboratory space, maintain a rotating stock of supplies.
  
• Plan and prioritize related purification activities.
  
• Analyze, interpret, and provide conclusions and present experimental data on internal meetings.
  
• Present periodic status updates to the group. Prepare technical reports, as needed.
  
• Communicate daily work in an organized lab notebook.
  
• Work closely with a team and communicate effectively to meet schedules and deadlines.
  
• Supervise colleagues in design and execution of experiments as needed.
  
• Conduct research that leads to publication in peer-reviewed journals and presentation of data at internal and external meetings.
  

Qualifications

Must-Have

• Master's Degree with 7+ years of industry experience or PhD (preferred)
  
• Extensive hands-on experience in protein purification techniques: chromatography, membrane filtration, centrifugation. Knowledge of biophysical characterization of biological molecules and analytical techniques. Familiarity with laboratory scale purifications chromatography systems (AKTA) and analytical instrumentation (HPLC, spectrophotometry, etc.). Knowledge of basic principles of process development, process scale up, validation, technical transfer.
  
• Proficiency in Microsoft systems such asOffice suite, Outlook, Etc.
  
• Knowledge and ability to independently design, plan, and execute protein purification activities.
  
• Ability to work independently and in teams.
  
• Lead and train junior scientists as needed.
  
• Ability to perform complex data analysis.
  
• Strong verbal and written communication skills are required.
  

Nice-to-Have

• Basic knowledge of DOE principals
  
• HTS instrumentation for protein purification process development
  
• Protein structure-functional analysis
  

PHYSICAL/MENTAL REQUIREMENTS

Must be able to lift at least 25 lbs.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

10% travel

Work Location Assignment:On Premise

Other Job Details:

Eligible for relocation package

Eligible for employee referral bonus

#LI-PFE

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development