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Discovery Postdoctoral Fellow, NPR1 Biology

Employer
Novartis
Location
Cambridge, Massachusetts, United States
Salary
Competitive
Closing date
Jun 6, 2023

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Discipline
Life Sciences, Biology
Position Type
Full Time
Job Type
Postdoc Fellowship
Organization Type
Pharma

Job Details

Job Description

1 Purpose...... to reimagine medicine. Join the Novartis Institutes for Biomedical Research (NIBR) as a Discovery Postdoctoral Fellow and contribute to unraveling one of the most important biological pathways contributing to hypertension, heart failure (HF), renal dysfunction and metabolic disease - the natriuretic peptide pathway.

NIBR is the innovation engine of Novartis. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.

Our Heart Failure discovery team within the department of Cardiovascular and Metabolic Diseases, in Cambridge, MA is seeking a highly motivated and team-oriented Postdoctoral Fellow to join our NPR1 program. The NPR1 signaling pathway is a fundamental contributor to hypertension and heart failure pathobiology, and drug candidates for this pathway are in clinical trials. NPR1 biology also is implicated in related indications that exacerbate HF, including chronic kidney disease, pulmonary arterial hypertension, and metabolic disease. As a Discovery Fellow, you will focus on deepening our fundamental understanding of NPR1 in one or more disease settings and carry out translational research to determine additional key indications of high unmet medical need. Multiple genetically engineered mouse models, surgical models and pharmacological tools are already available within the department. In addition, you will have access to experts across subject areas and platforms within NIBR, as well as academic experts in the field, and you will be encouraged to forge collaborations with these scientists. This is an outstanding opportunity to drive innovative, interdisciplinary research expected to be published in leading journals.

NIBR Fellows join our vibrant postdoctoral community for dedicated events, including the monthly postdoctoral seminars and our annual Research Day Symposium. All NIBR Fellows participate in our robust curriculum designed to develop scientific and professional skills. The postdoctoral term is for up to 4 years.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What You'll Bring to the Role:

* PhD in a relevant field such as Cardiovascular Physiology, Vascular Biology. Pharmacology, Molecular Biology, Biochemistry, Biophysics, or related field (PhD students in the last year of their thesis work are eligible to apply)
* A solid understanding of receptor-dependent signaling and second messenger systems.
* Experience with primary cell culture and/or animal models of HF, renal disease, pulmonary hypertension and/or metabolic disease a benefit.
* Demonstrated ability to work independently, and collaboratively with interdisciplinary research teams.
* Strong publication record or other scientific achievements (i.e. awards, patents)
* Excellent communication skills, both written and oral
* Passion for fundamental exploratory research and boundless curiosity

How to apply:

Please submit your CV and cover letter by June 30 for consideration.

For more information about our postdoctoral program, please visit https://www.novartis.com/careers/postdoc-program

Why Consider Novartis?

766 million. That’s how many lives our products touched in 2021. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how will we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore. Where you’re empowered to take smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

Imagine what you could do at Novartis!

Commitment to Diversity & Inclusion:

Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

The pay rate for this position at commencement of employment is expected to be $70,000 per year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. #PDX #CVMNIBR

Company

At Novartis, we are reimagining medicine.

Our purpose is to reimagine medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible.

Novartis has one of the industry’s most competitive pipelines. Many of these projects, which include new molecular entities as well as additional indications and different formulations for marketed products, are for medicines that could significantly advance treatment standards for patients worldwide.

We have entered an exciting era in health and biomedical innovation. Powered by our incredible colleagues, supported by our flexible-hybrid working model, new AI powered learning, personal growth and career platform and a refreshed commitment to diversity, equity & inclusion, we are well-poised to help lead this transformative moment for our industry and for ourselves. Join Us!

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