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Senior Associate Scientist - Chemical Biology

Cambridge, Massachusetts
Closing date
Jun 1, 2023

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Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

The Chemical Biology group plays a vital role in this mission as a key partner in the advancement of Pfizer's small molecule portfolio. We are seeking passionate and innovative scientists with experience in chemical biology/cell biology to join our world-class team in Cambridge MA. The successful candidate will have the opportunity to contribute to team goals and directly influence the discovery of Pfizer's future drugs. We are looking for ambitious scientists with a passion for teamwork, creativity, scientific excellence, and tenacity to see their work lead to First in Class medicines and scientific breakthroughs. As a colleague in the Chemical Biology group, your work will enable deeper understanding of the mechanism of action of our molecules and cellular targets in ensuring the best molecules/targets are advanced further to meet unmet medical needs.

How You Will Achieve It

  • Ability to work in highly collaborative, multidisciplinary teams
  • Desire to learn new skills (examples: cell assays, affinity enrichment, transfection)
  • Work under limited/moderate supervision and generate data to decipher small molecule/target mechanisms
  • Communicate effectively with team and present data/future directions at meetings
  • Effective time-management to meet agreed targets; develop plans for short-term work activities on own projects
  • Actively participate in all aspects of laboratory operations (examples: general housekeeping, cell culture, instrumentation upkeep & maintenance)



A qualified applicant holds a M.S (+0 yrs experience)/B.S (up to 2 years' experience) in biological sciences, chemical biology, analytical/organic chemistry, or a related field.


  • Highly skilled & collaborative laboratory experimentalist with a strong work ethic and experience of working on biological systems (cells/cell lysates/ex vivo tissues etc.).
  • Applied knowledge/expertise in analytical/purification techniques commonly used in chemical biology, for example: gel electrophoresis, Western Blots, antibody immunoprecipitation, ELISA, proteomics, molecular biology.
  • Excellent organizational, verbal and written communication skills, self-motivated and a team player capable to work in a flexible, matrixed team.

  • 0-2 Industry experience
  • Experience of working in the following areas would be desirable: click chemistry, affinity enrichment, cellular assays, chemo-proteomics, photoaffinity cross-linking, imaging.
  • Experience and knowledge in the operation and maintenance of different types of mass spectrometers (e.g. QExactives)


Laboratory-based role that includes walking, standing, lifting, carrying, pipetting etcetera.

Work Location Assignment: On Premise

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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