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Postdoc in AI/Bioinformatics for Single-Cell Omics and Cancer Therapeutics

University of Pittsburgh School of Medicine - Chiu Lab
University of Pittsburgh, Pittsburgh
Commensurate with experience
Closing date
Jul 21, 2023

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Life Sciences, Bioinformatics, Genomics, Cancer Research
Position Type
Full Time
Job Type
Postdoc, Postdoc Fellowship
Organization Type

Postdoctoral Associate position is available in the laboratory of Dr. Yu-Chiao Chiu at the Department of Medicine and UPMC Hillman Cancer Center at the University of Pittsburgh School of Medicine. The candidates will engage in bioinformatics research to systematically understand the biology of adult and pediatric cancers, to identify diagnostic and prognostic biomarkers, and to improve cancer therapy. Potential research topics include deep learning applications to spatial single cell profiles and multi-modal genomics and pharmacogenomics data. At the UPMC Hillman Cancer Center, the candidates will have the opportunity to build cross-disciplinary collaborations with clinical, translational, and basic scientists in order to bridge cutting-edge computational algorithms to unmet needs in precision oncology.


Our research

The Chiu Lab focuses on the development of state-of-the-art machine and deep learning models that integrate multi-modal genomic and pharmacogenomic data to study cancer biology and improve cancer therapy. Our latest works are well-recognized by broad cancer and bioinformatics communities, which include publications in Science Advances (selected by @NCIgenomics as the #1 paper of 2021), Briefings in Bioinformatics, and BMC Medical Genomics (selected as Springer Nature Highlight in Genetics), as well as presentations in the AACR 2023, ISMB 2023, and GLBIO 2023 conferences. Our lab has been very well funded by federal and other agencies, including the NIH (NCI R00), Hillman Developmental Pilot Program (NCI P30), Pittsburgh Liver Research Center (NIDDK P30), and The Fund for Innovation in Cancer Informatics. Please visit our lab website for more information.


Candidate qualifications

  • Highly motivated scientists who have recently earned a Ph.D. degree in bioinformatics, computational biology, electrical/computer/biomedical engineering, computer science, or a related field.
  • Strong experience in computational modeling of biological systems, large-scale cancer multi-omic datasets (TCGA, HTAN, TARGET, CCLE, etc.), high-throughput drug and genetic screens (DepMap, PRISM, GDSC, etc.), and common bioinformatics resources (NCBI, UCSC, Ensembl, etc.) is essential.
  • Experience in deep learning, machine learning, single-cell and spatial omics, and/or image processing is strongly desired.
  • Must be proficient with Linux and multiple bioinformatics programming languages, such as Python, R, MATLAB, and Perl.
  • Must possess excellent written and verbal English communication skills.


Career development opportunities

  • The PI has successful experience in acquiring the prestigious NIH/NCI K99/R00 Pathway to Independence Award and postdoctoral fellowships, as well as mentoring F99/K00 predoc to postdoc transition award application.
  • Candidates will receive dedicated mentorship on career development planning, career development awards, and postdoctoral fellowships such as the Hillman Postdoctoral Fellowships for Innovative Cancer Research (
  • Our lab members have cross-disciplinary experience spanning across engineering, informatics, biology, and medicine.


How to apply

Interested candidates should apply via (requisition #22005470) and submit their curriculum vitae, one-page research statement, and contact information of three references. Review of applications will start immediately and continue on a rolling basis until the position is filled. Inquiries may be directed to Yu-Chiao Chiu, PhD, Assistant Professor ( Individuals from underrepresented minorities or disadvantaged backgrounds are particularly encouraged to apply.


Institutional environment

The University of Pittsburgh is ranked #3 in the NIH funding. Pittsburgh has been consistently voted as one of the top livable cities in the US. The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human dignity, and diversity, EOE, including disability/vets.

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