Process Development (PD) Downstream Scientist
- Employer
- Spark Therapeutics
- Location
- Philadelphia, Pennsylvania. Hybrid and remote options available for select opportunities.
- Salary
- Salary not provided
- Closing date
- Jun 7, 2023
View more
- Discipline
- Health Sciences, Drug Development, Other, Manufacturing/QA/QC
- Job Type
- Staff Scientist
- Organization Type
- Pharma
Job Details
- Execute, evaluate, and interpret downstream process development experiments and provide recommendations based on scientific data.
- Utilize technical expertise and sound judgment for troubleshooting technical problems and finding appropriate solutions
- Evaluate, select, and apply sound engineering techniques and procedures to experimental design, execution, and analysis.
- Present findings in internal and external meetings, author technical reports and publications
- Effectively communicate with internal and external partners to progress projects
- Recent PhD or MS in chemical engineering, biochemistry, chemistry, biophysics, or related area with -0-4 year of experience
- Possess a fundamental understanding of protein biophysics, transport, and separations. Laboratory experience with protein separations is helpful.
- Fundamental knowledge of downstream process development of the biologics, such as viral vectors, monoclonal antibodies, vaccines, and recombinant proteins.
- Hands-on experience of AKTA, UPLC or equivalent system is helpful.
- Scientific publication record is plus.
- Have demonstrated the ability to think critically.
- A thorough understanding of protein biophysics, transport, and separations. Laboratory experience with protein separations is helpful.
- Ability to follow directions and independently perform experiments and data analysis.
- Attention to detail and precision in work
- Self-motivated, flexible, and willing to adapt to shifting priorities.
- Self-sufficient and able to work independently.
- Excellent communication, organization, and multi-tasking skills
- Must be able to lift 20 pounds
- Must be able to wear appropriate all Personal Protective Equipment
- Must be able to stand for long periods
Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.
Spark Therapeutics does not accept unsolicited resumes/candidate profiles from any source other than directly from candidates. Any unsolicited resume/candidate profile submitted through our website or to personal email accounts of employees of Spark Therapeutics are considered property of Spark Therapeutics and are not subject to payment of agency fees.
Nearest Major Market: Philadelphia
Join the Spark Team
We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now.
We don't follow footsteps. We create the path.
Learn more about Spark Therapeutics and view other openings.
Company
At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases.
Founded in March 2013 as a result of the technology and know-how accumulated over two decades at Children’s Hospital of Philadelphia (CHOP), our investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. This approach holds great promise in developing effective treatments to a host of inherited diseases. Our initial focus is on treating orphan diseases.
Headquartered in dynamic Philadelphia, we are a diverse, experienced team united in our goal to break down barriers for people and families affected by genetic diseases. As our name suggests, our investigational, one-time therapies are designed to spark healthy biology, and deliver potentially life-altering transformation for people and families affected by genetic disease. Spark is a member of the Roche Group.
- Website
- http://sparktx.com/
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