The Molecular NeuroTherapeutics Laboratory at Department of Neuroscience, Mayo Clinic Florida is seeking applications from qualified postdoctoral candidates with expertise in neuroscience, and animal model for the NIH funded study to investigate the therapeutic efficacy of antisense oligonucleotides (ASO) on Alzheimer’s disease mouse model and patient-derived induced pluripotent stem cell (iPSC) models.
Our focus of the research is to invent therapeutics to delay tau pathology development during the early stage of Alzheimer's disease. One of these therapeutic targets is neuron and microglia-specific molecules. The postdoc for this position will investigate the therapeutic efficacy of ASO by assessing the tau pathology development and animal behavior with tauopathy mouse model and patient derived iPSC-derived neurons, microglia, and organoid models.
The research will be based at the brand-new lab at Department of Neuroscience, Mayo Clinic Florida, supported by world-class level lab equipment as well as core facilities. Ikezu lab has connected with many prestigious collaborators in the world to enhance research activity and acquire cutting edge knowledge.
Each applicant must possess an advanced degree (Ph.D.) in a relevant field with less than 5 years of postdoc experiences. The ideal candidates will have expertise in animal models of neurodegenerative diseases, animal surgeries, confocal microscope imaging and/or biochemistry, iPSC, and organoid culture. The ideal candidates also should be team players with high scientific standards and communication skills, and have the ability to work in an interactive, fast-paced environment.
The accepted candidate will be trained to work independently. They are expected to keep records and data of all scientific experiments according to established procedures, occasionally supervise students, act as a source of information and advice to other members of the group on scientific protocols and experimental techniques. They will have opportunities to draft technical reports, manuscripts for scientific journals, and present work internally and externally as needed for their career development.
The following links provide more information about the laboratory and institution:
Molecular NeuroTherapeutics Laboratory: https://www.mayo.edu/research/labs/molecular-neurotherapeutics/overview
Department of Neuroscience, Mayo Clinic Florida: https://www.mayo.edu/research/departments-divisions/department-neuroscience-florida/overview
To inquire, please send the following files to email@example.com: Curriculum vitae (including publication list), a statement of research interest including brief description of past work, and contact information of three references.