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Postdoctoral Fellow Position in Cancer Biology

Employer
University Maryland Eastern Shore School of Pharmacy
Location
Maryland
Salary
Salary (commensurate with experience) plus comprehensive fringe benefits
Closing date
Apr 14, 2023

NIH-funded Postdoctoral fellow position is available immediately in Department of Pharmaceutical Sciences at University of Maryland Eastern Shore School of Pharmacy (UMES SOP) for outstanding candidate(s) interested in cancer biology or translational cancer research. Our laboratory is interested in identification of the RNA risk elements (aberrant RNA splice variants and deregulated microRNAs) in cancers, and aims to study how these oncogenic RNA risk factors contribute to the cancer aggressiveness and drug resistance (see Nature Communications 8:15921, Cancers 2023, 15:1337; Cancers 10. Pii: E458; Clin. Cancer Res. 21:4970-4984, Int. J. Mol. Sci. 23, 9643; Intl. J. Mol. Sci. 23:2926; Mol. Cancer Res. 17:2115-2125; Surgery 170:1160-1167). We have a particular focus on the functional impacts of these oncogenic splice variants/microRNAs in activation of PI3K/AKT/mTOR, VEGF, and mTOR/AR signaling pathways. Our work encompasses a wide range of in vitro and in vivo experimental techniques including gene expression, protein biochemistry, signaling transduction, gene knockdown, cell-based functional assays, mouse xenograft, organoid models, immunohistology, genomics/bioinformatics, proteomics, drug screening and interrogation of clinical samples. We are also involved in several genetic/pharmacological efforts to develop precision biomarkers and novel therapeutic targets for cancers. UMES SOP is a highly collaborative environment and our laboratory is involved in collaborations with multiple other research programs within the scientific community including programs in systems biology, high-throughput drug discovery, cancer pathology and pharmacology. The PI is affiliated with UMES SOP and University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC), and the postdoctoral fellow will be trained through a collaborative program at UMES SOP, UMGCCC, and Diet, Genomics and Immunology Laboratory at USDA. We are also actively engaged in translating our laboratory-derived findings into clinical setting conducted at the UMGCCC. We provide an excellent research/career development environment, and competitive salary and fringe benefits. Highly motivated candidates with a PhD, MD, or MD/PhD degree (degree obtained within 2 years) and a strong background in molecular biology and cancer biology please send CV to Dr. Peter Wang at bwang@umes.edu

UMES is an EEO/AA employer and will not discriminate against any employee or applicant because of race, age, sex, color, sexual orientation, religion, national origin, marital status, genetic information, or political affiliation. Minorities, women, veterans, and persons with disabilities are encouraged to apply. The successful candidate must be able to show acceptable documentation establishing the right to accept employment in the United States of America without employer sponsorship.

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