Senior Scientist, Influenza Biofunctional Assays, Vaccines

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.

Pfizer's Vaccine Research and Development organization has been at the forefront of making history and improving human health - including creating some of the most complex and most sophisticated vaccines in the world, designed to tackle a wide range of infectious diseases of large unmet medical needs in people of all ages.

ROLE SUMMARY

The High-throughput Clinical Immunoassays & Diagnostics (HCID) group within Pfizer Vaccines R&D is seeking a biologist with experience in the development of neutralization assays for a Senior Scientist role in the Neutralization Assay Group. This role will be responsible primarily for the Phase 3 clinical testing for the influenza HAI (hemagglutination inhibition assay) and may support other assays within the group.

You will function as a senior member of the Influenza Biofunctional Assay Group and manage a small team. As an integral member of this dynamic team, the incumbent must have a strong work ethic and be highly collaborative with the other group members. All work is to be done in a compliant manner according to relevant SOP guidelines and GLP and/or GCLP guidelines, when required. You will author and review documentation to support the group, reagent qualification reports, and prepare internal and external presentations. This position will ensure business-critical deadlines are met and communicate progress to senior leaders. The responsibilities also include reviewing clinical data and quality control data to monitor assay performance.

As this role is a part of a dynamic team, the incumbent should possess a strong work ethic and collaborative spirit. Collaborations across multidisciplinary teams that include Clinical & Diagnostic Assay Development, Cell Culture Team, Automation Group, Project Management, Quality Assurance, Research Informatics, and Statistics, as well as appropriate partner lines.

ROLE RESPONSIBILITIES

• Support clinical testing for the influenza HAI, manage the training of entry level scientists, and manage strategies for the execution of clinical testing to meet program timelines.
• Perform experiments related to the development and optimization of biofunctional assays to increase program throughput.
• Write and review reports supporting the life cycle of the assay, including assay test methods, reagent qualifications, and other supportive documentation.
• Assist in the preparation and qualification of new reagents.
• Assist in updating and writing documents including standard operating procedures, test methods, reagent reports, and data archiving.
• Oversee the review of clinical data packages.
• Oversee the maintenance of the laboratory, including ordering/ restocking supplies, updating reagent inventory, and ensuring cleanliness.
• Provide scientific input on experimental design and data analysis.
• Supervise activities of direct reports, provide scientific leadership within the neutralization assay group, and foster teamwork, trust, and coaching among group members.
• Provide scientific strategy, analyze experimental data, draw conclusions, and propose future research plans.
• Communicate experimental results at team meetings with group members and senior management.
• Stay current on scientific and technical literature and attend relevant scientific meetings to apply new technologies and/or scientific principles.
• Apply GCLP guidelines to assay development and sample analysis.
• Participate and organize cross-functional team meetings.

BASIC QUALIFICATIONS

• PhD with Post Doc experience or MS with 7+ years relevant industry experience.
• A strong background in virology, immunology, microbiology, or a related field is essential.
• Familiarity with assay qualification/validation and system suitability/acceptance criteria.
• Experience working in high-throughput testing laboratories operating under GLP guidelines, including SOPs, instrument IOQ/PQ, and good documentation practices.
• Demonstrated leadership ability through project management and mentoring.
• Proven delivery of objectives in a complex matrix environment.
• Ability to thrive in fast-paced, changing environment.
• Excellent verbal and written communication skills.
• Proficiency with Excel, PowerPoint, and statistical software including GraphPad Prism.

PHYSICAL/MENTAL REQUIREMENTS

The position has physical requirements of basic office and laboratory work (sitting, standing, and walking). The mental requirements include the ability to analyze data and design experiments; to present complex concepts to colleagues.

Relocation support available

Relocation assistance may be available based on business needs and/or eligibility.

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development