Scientist I - Oral Biologics

Novo Nordisk
Lexington, Massachusetts
Commensurate with experience
Closing date
Apr 5, 2023

Scientist I - Oral Biologics

Facility:  Research


Lexington, MA, US

About the Department                                                                                                                                 

As part of the establishment of our R&D Hub in greater Boston, Novo Nordisk is growing its efforts within advanced drug delivery. A cornerstone of this is an expansion of our efforts in advancing oral biologics-based treatments to address unmet needs within a broad range of serious chronic diseases. Building on our success in developing the world’s first GLP-1 peptide in a tablet, we are rapidly growing our activities in our relentless pursuit of the next generation of oral-based therapies across a range of new modalities. 
You will join and help build a vibrant and science-focused team of scientists, where innovation is at the core. One of the core focuses of the hub is to drive early-stage innovation within oral drug delivery sciences with a focus on new modalities such as peptides, proteins and oligonucleotides. In growing our presence in the greater Boston area via our R&D Hub, we seek to bring together the 100-year heritage and experience of Novo Nordisk with the unparalleled innovation eco-system found in Boston.
We will be based in new, purpose-built lab facilities in Lexington and co-located with our Dicerna Transformational Research Unit (TRU). As part of a team of leading scientists and innovators, you will bring your own ideas and collaborate with others to develop the next generation of oral biologics. It’s ground-breaking work with the promise of improving the lives of millions of people with chronic conditions. If you want to make a difference, join us to do pioneering research that can impact people everywhere.


The Position

The Scientist I will provide major contributions to the identification and development of novel advanced drug delivery systems  to achieve oral administration of biologics including peptides and proteins. This will be achieved by independently designing and executing experiments, coordinating with cross-functional teams, and ensuring completion of project key deliverables. The Scientist will represent the organization to the external scientific community through publication and presentation of research and through participation in external collaborations.


Internal relationships include project teams and research colleagues both in Denmark, other US based teams and around the globe. It is crucial that the holder of the role will have daily proactive collaboration with colleagues in the team, together with close colleagues based in Denmark. Communicates data externally when required. May oversee parts of Advanced Drug Delivery Hub operations and laboratory facilities. Individual Contributor: does not manage other employees or contingent workers.


Essential Functions

  • Advances research projects by demonstrating technical expertise and creativity in oral drug delivery, and broad knowledge of related disciplines.
  • Analyzes complex data with high degree of sophistication, connecting disparate datasets to reach conclusions and set direction on experiments. Contributes strong scientific acumen to enable projects and advance the research agenda.
  • Effectively communicates and collaborates across global sites and guides project strategy by providing expert input to cross-functional project teams. May represent the organization at external conferences and by contributing to publication of scientific papers and patents. Participates in external collaborations.
  • Maintains a strong understanding of theoretical knowledge and a connection to the external scientific community through continuous evaluation of relevant literature. Expands the capabilities of oral drug delivery sciences through the generation of new ideas, evaluation of oral drug delivery methodologies, and implementation of technologies that add value.
  • Leads cross-functional experimental teams to achieve project goals, mentor junior staff, and provide training.
  • Influences the research pipeline by contributing recommendations to new project planning



  • Bachelor's Degree required. Degree within pharmaceutical sciences preferred
  • Doctoral degree with 2+ years’ post-doctoral and/or industry relevant experience, OR Master’s degree with 8+ years’ relevant experience OR Bachelor's with 12+ years’ relevant experience can also be considered
  • Relevant required experience includes:
    • Hands-on experience with solid dosage forms (e.g., tablets, capsules)
    • In-depth knowledge of core formulation techniques (e.g., spray drying, granulation etc.,)
    • Understanding of the physiology of the gastrointestinal tract
    • The successful candidate must be a resourceful and proactive individual who is able to work as a team player in a dynamic environment with tight deadlines
    • Strong analytical, verbal and written communication skills, as well as attention to detail
  • Preferred experience includes:
    • Experience in formulating new modalities (e.g., peptides, proteins, oligonucleotides)
    • Expert knowledge and fluent understanding in the operation and maintenance of a variety of HPLC instrumentation
    • Knowledge of permeation-enhancing excipients
    • Experience of a variety of solid-state characterization techniques
    • Understanding of active transport-based mechanisms for absorption across the gastrointestinal tract
  • Demonstrates excellent verbal and written communication skills


We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.


At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.


Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.


Novo Nordisk requires all new hires to be fully vaccinated against COVID-19 prior to the first date of employment. As required by applicable law, Novo Nordisk will consider requests for reasonable accommodation.


If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.

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