Sr Mgr/Team Lead, PPT Chemistry/Engineering, Isolations/Safety

Kalamazoo, Michigan
Closing date
Apr 1, 2023

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Life Sciences, Physical Sciences, Engineering, Analytical Chemistry
Position Type
Full Time
Organization Type
Why Patients Need You

Whether you are involved in the design and development of manufacturing processes for products or supporting maintenance and reliability, engineering is vital to making sure customers and patients have the medicines they need, when they need them. Working with our innovative engineering team, you will help bring medicines to the world even faster by imagining what's possible and taking action.

What You Will Achieve

The Senior Manager, PPT Chemistry/Engineering, Isolations/Safety will lead and manage a team of scientists. Key leadership accountabilities for this role will be process safety evaluations, isolation development and support, fermentation and isolation costing, product/process technical stewardship, people leadership, technical problem solving, and assure the best service is provided to site operational teams. The effective manager will oversee and guide the team in its responsibilities which will include: Perform production troubleshooting and support, process improvements for the API isolations, serving as primary technical experts for the manufacturing methods, performing scientific laboratory studies, and making recommendations to improve manufacturing reliability, cost, safety, compliance, and environmental performance. Working closely with the manufacturing plant, reviewing procedures, reviewing process performance data, and solving process problems. The team is also expected to provide technical knowledge, expertise, evaluation for other support functions. The leader will oversee exploratory research to produce new knowledge on current and developmental processes, and execute ideas and plans to increase productivity. To ensure research proposals are technically and economically sound for developing and evaluating improved isolations, equipment, and processes. They will report progress of research work and significance of the results. Recommends utilization of the results or changes in the scope of work or termination of projects. A successful candidate will have significant prior experience, scale up of chemistry and isolation processes, costing, customer interactions, equipment cleaning, and a track-record of collaborating & innovating with cross-functional teams. They will work with the leaders and staff from the other PPT Chemistry/Engineering teams to ensure projects, both PC1 and PGS internal, are fully supported and that timely support is given to address Plant challenges. The PPT Chemistry/Engineering, Isolations/Safety will report to the PPT Chemistry/Engineering leader.

How You Will Achieve It

The PPT Chemistry/Engineering, Isolations/Safety may be assigned to lead and/or assist in the development of ad-hoc projects outside of their day-to-day responsibilities. However, core responsibilities include the following:
  • Lead safety lab
  • Lead/review interpret safety data for new processes
  • Lead the development of isolation processes
  • Develop and lead PPT's expertise in sterilization
  • Assist process development on scale up and engineering related issues
  • Assist PPT Chemistry/Engineering Supply Assurance leader as needed for the scale up lab
  • Engineering representative on safety issues and run large reviews.
  • Active advisor for the plant on new processing equipment and engineering technologies
  • People and technical leadership support to PPT Chemistry/Engineering Isolations/Safety team.
  • Actively involved in daily operations.
  • Partner with Operations, Engineering, Quality, Safety, Supply Chain and other site and global colleagues to meet the production schedules, ensure technical excellence, commercial supply, uphold quality standards, driving towards zero defects.
  • Attend/lead meetings with the plant on current issues/programs and keep upper management informed.
  • Ensures quality data is gathered to assist in making process recommendations to the plant
  • Recognize ongoing training/development needs to continually ensure the develop their staff and capabilities to ensure a high-level scientific expertise.
  • Identifies new tools/ technology/ processes that aid in the achievement of performance standards
  • Applies extensive technical and industry-specific and non-specific expertise and has full knowledge of the requirements of other related disciplines (technical, Regulatory, QO, Project Management, etcetera).
  • Able to adapt and respond positively to a variety of situations and people in order to meet changing work unit priorities
  • Decisions impact the achievement of objectives and the reputation of the department, and actions help to set the reputation of the department.
  • Monitors and manages the efforts of colleagues to achieve delivery of short-term to mid-term goals.
  • Leads and motivates others, generating commitment and a shared sense of purpose. Enables others to contribute their best.
  • Acts as technical mentor who engages talent to meet objectives.
  • Acts as an advisor to management, offering recommendations and assessments, and often owning drive for decisions and implementation.

All activity will be performed consistently with Pfizer's mission, values, and applicable policies and guidance.


  • Applicant must have a Bachelors degree with at least 7 years of experience OR Masters degree with more than 6 years of experience, OR a PhD with 2+ years of experience
  • Experience leading teams of scientists with varying levels of experience and formal education (BS/MS and/or PhD).
  • Extensive experience evaluating new plant processes and technologies
  • Experience in project proposals and assessments
  • Extensive experience with safety evaluation of new processes
  • Extensive understanding/evaluating thermodynamic data on intermediates/products/reactions
  • Extensive experience working with Regulatory, Quality, Project Management, and Safety
  • Candidate has demonstrated a diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

  • BS/BA in related field and 10+ years of e xperience in supporting scale-up and technology transfer to pilot or commercial scale facilities.
  • Significant experience in kilo lab operations and safety review
  • Significant experience in plant operations.

Physical/Mental Requirements

Position involves considerable standing in the laboratory, working with the hands and arms, and computer work.

Must be able to work with a variety of chemical and biological materials, and in chemical manufacturing facilities.

Non-Standard Work Schedule, Travel or Environment Requirements

Must be able to work non-regular schedules as needed to accommodate the needs of laboratory and production operations.

Work Location Assignment:On Premise

Other Job Details
  • Last Date to Apply: March 28, 2023
  • Eligible for Relocation Package: Yes

Relocation assistance may be available based on business needs and/or eligibility.

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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