Research Investigator - Lung Cancer Sequencing

University of Texas MD Anderson Cancer Center
Houston, Texas
Closing date
Apr 1, 2023

View more

Health Sciences
Organization Type

Job Details


The Research Investigator (RI) will help a vibrant laboratory focused on lung cancer development with various experiments. The RI will assist in processing human airway and lung tissue samples for bulk and single-cell sequencing analyses. The RI will also aid in spatial transcriptomics of normal and cancer tissues. The RI will help processing fresh human and murine tissue samples for producing single-cell RNA and TCR/BCR libraries. The RI will also assist in performing validation by immunohistochemistry and other imaging techniques.


Caring Behaviors
  • Courtesy: Is respectful and courteous to each other at all times.
  • Friendliness/Teamwork: Promotes and rewards teamwork and inclusiveness; is sensitive to the concerns of our patients and our co-workers.

Integrity Behaviors
  • Reliability: Communicates frequently, honestly and openly.
  • Accountability: Holds self and others accountable for practicing our values.
  • Safety: Models safe behavior (wears badge and personal protective equipment, washes hands, and keeps work area clean and orderly); Notices a safety concern or emergency, understands role and uses proper procedures to report it; Mitigates risk to the institution through sound business practices; Demonstrates ethical and personal responsibility in work and behavior

Discovery Behaviors
  • Responsiveness: By his/her actions, creates an environment of trust; Encourages learning, creativity and new ideas.
  • Personal Leadership/Self-Initiative: Helps others to identify and solve problems; Seeks personal growth and enables others to do so.


Technical Functions Function in an independent manner, and have the ability to design research experiments.
Discusses goals of each project with supervisor; with the help of supervisor, develops a step-by-step written procedure outlining the specific actions required to conduct the experiment before proceeding
Ability to work on several research projects concurrently in an independent manner
Compile research data and submit results to for inclusion in publications, grants or protocols.

Laboratory Operation The Research Investigator will be responsible for the following laboratory operations:
Processing fresh and frozen human airway and lung tissue samples for bulk and single-cell sequencing analyses.

Processing fresh normal and cancer tissues for generation of libraries for spatial transcriptomics as well as single-cell RNA and TCR/BCR sequencing.

Perform validation of targets by immunohistochemistry, flow cytometry, and imaging techniques.

Provide technical and coordination expertise in carrying out various research projects, coordinates procedures, and performs technical laboratory duties in accordance with general and/or specific plans.

Collaboration and Presentation Interacts and participates in collaborative studies inside and outside MD Anderson.
Trains other research personnel and students on established assays, and use of laboratory equipment
Presents research data at internal and external meetings and conferences
Prepare final reports in the format requested for the data generated by suggested due date
Willingness to learn and to help others in the implementation of new techniques

Data Maintenance Enter and maintain data from research activities in notebook/computer databases as appropriate.
Performs and documents all required quality control/quality assurance.
Maintains accurate, detailed records and experimental data and protocols
Prepares graphs, slides and tables via photography, computer, or manually.
Collaborates or assists supervisor and senior research staff with preparation of reports and grant requests.
Acquires and maintains proficiency in computer functions.
Able to work with database, graphing and word processing computer programs such as Microsoft Excel, Power Point, Word and Prism
Must be able to fully communicate results and understand instructions from principal investigator and colleagues.

Other duties as assigned

Bachelor's degree in one of the natural sciences or related field. Five years of experience in scientific or experimental research work. With preferred degree, three years of required experience. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.


The University of Texas MD Anderson Cancer Center in Houston is one of the world's most respected centers focused on cancer patient care, research, education and prevention. It was named the nation's No. 1 hospital for cancer care in U.S. News & World Report's 2023 rankings. It is one of the nation's original three comprehensive cancer centers designated by the National Cancer Institute.

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert