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Postdoctoral fellow, Microbial small molecules and Nuclear receptor targets

Employer
Henry Krause lab
Location
Toronto (City), Ontario (CA)
Salary
$55,000 per year plus benefits
Closing date
Apr 30, 2023

View more

Discipline
Life Sciences, Molecular Biology
Position Type
Full Time
Job Type
Postdoc Fellowship
Organization Type
Academia

We are looking for a PDF to help isolate and identify metabolites produced by intestinal microbes that bind and modulate nuclear receptor proteins. Our pipeline consists of all 48 human nuclear receptors and a variety of gut and microbial extract preparations. Identified interactions will be tested for roles in host metabolism, inflammatory and other disorders. Our approach is described in: Liu et al, 2022, Science Signaling; 15 (741), eabo1857. Individuals with experience in proteomics and small molecule chemistry will be particularly well qualified.

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