Principal Scientist-Biotech/Vaccines

ROLE SUMMARY

This individual will be responsible for supporting manufacture of materials for Viral strain change within the Vaccine Research and Development - Early Bioprocess Development group. This individual will plan and execute all activities required to manufacture DNA template, RNA drug substance, and LNP drug product to support strain changes as required. The individual will provide leadership, scientific and technical support for the team of process scientists, as well as work with multifunctional teams outside of their reporting structure. Manage a group of up to six peopel.

• Effectively plan for and execute a manufacturing campaign to deliver the DNA template, RNA drug substance and LNP drug product to support viral vaccine stain change.
• Follows existing SOPs and methods to manufacture and release materials including critical reagents (polycloncal antibodies). Responsible for reviewing batch records and in-process data. Works directly with analysts to actively trouble-shoot activities.
• Partner with the Analytical strain change team throughout the year to actively de-risk campaigns to deliver quality materials on-time and right first time. Communicates effectively to the stakeholders regarding potential delays or material quality issues.
• Publish all required documents (CoAs, batch records, production reports, etc.) to support a manufacturing campaign.
• Provide management and supervision of colleagues, the group budget, laboratories and compliance.
• Complete all required trainings in compliance with departmental requirements and follow appropriate safety practices in the workplace.

BASIC QUALIFICATIONS

• PhD degree in Chemical/Biochemical engineering, Biochemistry, Chemistry or related discipline with at least 4 years industry experience or an MS in the same disciplines with over 9 years of industry experience.
• Extensive experience in bioprocess manufacturing of vaccine and biopharmaceutical products.
• 1-4 years of Management experience a plus
• In-depth knowledge and hands on experience of various unit operations of drug substance and drug product manufacture.
• Proficiency with personal computers, word processing, spreadsheets, PowerPoint and other relevant scientific software is required.
• Strong verbal and written communication skills

PREFERRED QUALIFICATIONS

• Practical experience with manufacturing an RNA vaccine from DNA template to RNA drug substance and LNP drug product is preferred.

PHYSICAL/MENTAL REQUIREMENTS

Standard laboratory conditions - sitting, standing, lab based

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

40 hours per week.

Relocation support available

Work Location Assignment:Flexible

Relocation assistance may be available based on business needs and/or eligibility.

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development