Principal Scientist, Diagnostics

Pearl River, New York
Closing date
Apr 6, 2023

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Health Sciences, Diagnostics, Drug Development
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
Role Summary

The High-throughput Clinical Immunoassays & Diagnostics' (HCID's) Diagnostics group within Pfizer's Vaccine Research and Development (VRD) organization is seeking a scientist with extensive experience in diagnostics assay validation. As a principal scientist, the individual will be responsible for the successful execution of validation activities related to diagnostics assays used in Pfizer's vaccine clinical trials. This individual will also work closely with cross-functional teams to ensure diagnostic assay methods are successfully validated and transferred in a timely manner to support vaccine clinical studies and advance Pfizer's vaccine portfolio.

Role Responsibilities

  • Responsible for the successful and timely execution of validation experiments, QC of data, and statistical analyses.

  • Develop validation plans, protocols, and reports.

  • Design reagent qualification methods and acceptance criteria.

  • Responsible for assay transfers and developing assay experts within the Diagnostics team.

  • Contribute to the development of documentation supporting the life cycle of the assay.

  • Support ongoing clinical testing, including troubleshooting technical issues and addressing queries from regulatory agencies

  • Provide scientific leadership and strategy, analyze experimental data, draw conclusions, and propose future research plans

  • Communicate experimental results at team meetings and with senior management

  • Participate and organize cross-functional team meetings

Basic Qualifications

  • PhD with 4+ years of relevant industry experience

  • Demonstrated experience in molecular and/or serological diagnostic assay development and validation

  • Experience with authoring SOPs and assay validation plans/reports

  • Strong communication and interpersonal skills with demonstrated ability to drive, manage and deliver results in cross-functional projects

Preferred Qualifications

  • Experience with automating testing workflows and use of laboratory automation systems
  • Training in a GCLP environment and regulatory guidelines


Ability to perform work while standing/sitting.


  • This position may require occasional weekend and evening work to meet critical business timelines.

  • This position may require occasional travel between Pfizer sites and other business-related travel.

Work Location Assignment:On Premise

Other Job Details:

Eligible for relocation package

Eligible for employee referral bonus


Relocation assistance may be available based on business needs and/or eligibility.

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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