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Principal Scientist - Complement-related Therapeutics (80-100%*)

Employer
Novartis
Location
Basel, Switzerland
Salary
Competitive
Closing date
Feb 18, 2023

View more

Discipline
Health Sciences, Drug Development
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
Pharma

Job Details

Job Description

1 out of 10 people are suffering from immunological diseases. The Immunology Disease Area at the Novartis Institutes for Biomedical Research (NIBR) is investing in the discovery of novel and transformative therapies to improve the life of affected patients. As part of this effort, we are seeking an innovative and highly motivated Principal Scientist or Senior Principal Scientist to guide discovery approaches in the field of complement with a focus on small molecule drugs.

Your responsibilities will include but not be restricted to:

You will be responsible for leading a state-of-the-art laboratory of BSc/MSc level scientists to discover and develop small molecule complement inhibitors for a number of autoimmune and inflammatory diseases. This will include the use of enzymatic, biophysical, biochemical, and cellular assays to identify and characterize novel inhibitors and to discover appropriate biomarkers for monitoring complement activation in various tissues.
• Contribute to and/or lead early drug discovery projects within multidisciplinary teams up to clinical proof-of-concept studies in patients
• Define and execute on innovative scientific strategies, test novel disease-relevant hypotheses and develop transformative therapies
• Closely collaborate with scientists, clinicians, and technology experts across different departments in the global organization.

Diversity & Inclusion / EEO

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Minimum Requirements

What you will bring to the role:

• A PhD degree with a minimum of 2-3 years of postdoctoral experience in biochemistry, protein science and immunology
• Significant scientific accomplishments and successful collaborations documented by publications in high-impact journals
• Strong technical and theoretical background/expertise in complement biology, innate immunity, and translational research
• Proven track record of leadership, strategic thinking, creativity, and risk taking
• Excellent organization, communication, presentation and analytical skills

Desirable requirements:
• Experience as an independent research scientist in an academic setting and/or in the pharmaceutical/biotech sector
• Proven success in independently initiating and leading interdisciplinary research projects

Why Novartis?

769 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

* This position is eligible for 80-100%* working time, however, some restrictions on flexible working options may apply and will be discussed during interview if applicable.

Join our Novartis Network:

If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

Company

At Novartis, we are reimagining medicine.

Our purpose is to reimagine medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible.

Novartis has one of the industry’s most competitive pipelines. Many of these projects, which include new molecular entities as well as additional indications and different formulations for marketed products, are for medicines that could significantly advance treatment standards for patients worldwide.

We have entered an exciting era in health and biomedical innovation. Powered by our incredible colleagues, supported by our flexible-hybrid working model, new AI powered learning, personal growth and career platform and a refreshed commitment to diversity, equity & inclusion, we are well-poised to help lead this transformative moment for our industry and for ourselves. Join Us!

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