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Postdoctoral Fellow

Tulane Med School
New Orleans, Louisiana
Commensurate with experience
Closing date
Mar 3, 2023

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Life Sciences, Biochemistry, Microbiology, Molecular Biology
Position Type
Full Time
Job Type
Postdoc, Postdoc Fellowship
Organization Type

POSITION SUMMARY:   The Postdoctoral Fellow for the Department of Biochemistry and Molecular Biology will be responsible for developing in vitro diagnosis technologies and approaches to detect and measure biomarkers associated with important human diseases and to employ these methods to analyze samples from animal models of human disease and human subjects to test and validate their performance.


  1. Recent Ph.D. in any field of biosensor, bioengineering, material science, nano-/micro-technology, nanopore sequencing (especially for peptide identification), mass spectrometry, proteomics, engineered multi-omics or related field, with demonstrated skills in biosensor design and fabrication, nanobiosensors, machine learning, protein chemistry, peptide sequencing, MALDI, LC-MS/MS, bioinformatics and biostatistics.

2.  Research experience in biosensor design and development, lab on a chip, microfluidic system, point of care tests, biomarker discovery, studies on extracellular vesicles or nano/micro scale liquid chromatography, electrospray ionization, high resolution mass spectrometry, protein biochemistry, top-down and bottom-up proteomics including project design, sample preparation and data analysis, PTM identification.


  1. Proficient research skills and the ability to perform nanomaterial design and fabrication, cell proliferation/growth, standard molecular biology techniques, protein and exosome isolation, mass spectrometry analyses, or other such related experimental techniques.
  2. Strong computer skills, including an advanced working knowledge of Microsoft Word, Excel, and/or Power Point software applications. Design and development of scientific graph are highly preferred.
  3. Skills in biostatistical analysis and machine learning are desired.
  4. Solid analytical skills and attention to detail; ability to read literature and understand its content with analytic mind.
  5. Motivation to independently work on research assignments and create new projects, as assigned by the PI.
  6. Excellent verbal and written communication skills.
  7. Excellent organizational skills.
  8. Excellent interpersonal skills.
  9. Ability to multi-task and prioritize work assignments.
  10. Ability to maintain confidentiality in all work performed.
  11. Ability to give oral presentation of experimental results in lab meetings and research conferences.
  12. Ability to review journal manuscripts and provide critiques.


Ability to complete and pass successfully the required occupational health screening referenced in the University’s Animal Handler Health Surveillance Program on an annual basis.


  1. Zheng, W., LaCourse, S., Song, B., Singh, D. K., Khanna, M., Olivo, J., Stern, J., Escudero, J., Vergara, C., Zhang, F., Li, S., Wang, S., Cranmer, L.M., Huang, Z., Bojanowsk, C.M., Bao, D., Njuguna, I., Xiao, Y., Wamalwa, D. C., Nguyen, D. T., Yang, L., Maleche-Obimbo, E., Nguyen, N., Zhang, L., Phan, H., Fan, J., Ning, B., Li, C., Lyon, C. J., Graviss, E. A., John-Stewart, G., Mitchell, C. D., Ramsay, A. J., Kaushal , D., Liang, R., Pérez-Then, E., Hu, T.* Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples. Nature Biomedical Engineering. 2022. 6, 979-991.
  2. Huang, Z., LaCourse, S., Kay A.,  Stern, J., Escudero, J., Youngquist, B., Zheng, W., Vambe, D., Dlamini, M., Mtetwa, G., Cranmer, L., Njuguna, I., Wamalwa, D., Maleche-Obimbo, E., Catanzaro, D., Lyon, C., John-Stewart, G., DiNardo, A., Mandalakas, A., Ning, B.,  Hu, T.* CRISPR Detection of Circulating Cell-free M. tuberculosis DNA in Adults and Children, Including Children with HIV. The Lancet Microbe. 2022, 3(7): E482-492.
  3. Zheng, W., Shu, Q., Mao L., Lyon, C., Li, C., Hu, T.* Nanopore-based disease diagnosis using pathogen-derived tryptic peptides from serum. Nano Today. 2022, 45:101515.
  4. Ning, B., Youngquist, B. M., Li, D. D., Lyon, C. J., Zelazny, A., Maness4, N. J., Tian, D., Hu, T.* Rapid detection of multiple SARS-CoV-2 variants of concern by PAM-targeting Mutations. Cell Reports Method. 20222(2):100173.
  5. Ning, B., Chandra, S., Rosen, J., Evan, M., Melvin, A., Lane, P., Ivy, T., Brittany, S., Escarra, M., Stacy, D., Zwezdary, K., Lyon, C., Norton, E., Hu, T.* Evaluation of pathogen specific T-cell activation with a point-of-care on-chip IGRA. ACS Nano. 2022, Accepted.
  6. Ning, B., Huang, Z., Youngquist, B. M, Scott, J. W., Niu, A., Bojanowski, C., M., Zwezdaryk, K. J., Saba, N., S., Fan, J., Yin, X., Cao, J., Lyon, C. J., Li, C., Roy, C. J., Hu, T.* Liposome-mediated detection of SARS-CoV-2 RNA-positive extracellular vesicles in plasma. Nature Nanotechnology. 2021. 16, 1039-1044.
  7. Ning, B., Yu, T., Zhang, S., Huang, Z., Tian, D., Lin, Z., Niu, A., Golden, N., Hensley, K., Threeton, B., Lyon, C. J., Yin, X., Saba, N., Rappaport, J., Wei, Q., Hu, T.* A smartphone-read ultrasensitive and quantitative saliva test for COVID-19. Science Advances. 2021. 7(2): eabe3703.
  8. Huang, Z., Ning, B., Yang, H., Youngquist, B., Niu, A., Lyon, C., Beddingfield, B., Fears, A., Monk, C., Murrell, A., Bilton, S., Linhuber, J., Norton, E., Dietrich, M., Lai, W., Scott, J., Yin, X., Rappaport, J., Robinson, J., Saba, N., Roy, C., Zwezdaryk, K., Zhao, Z., Hu, T.* Sensitive tracking of viral RNA in plasma through all stages of SARS-CoV-2 infection. J. Clinical Investigation. 2021, 131(7):e146031.
  9. Liu, Y., Fan, J., Xu, T., Ahmadinejad, N., Hess, K., Lin, S., Zhang, J., Liu, X., Liu, X., Ning, B., Liao, Z., Hu, T.* Extracellular Vesicle Tetraspanin-8 Expression Predicts Distant Metastasis in Non-Small Cell Lung Cancer after Concurrent Chemoradiation. Science Advances. 2020, 6:11, eaaz6162.
  10. Rodrigues, M., Richards, N., Ning, B., Lyon, C., Hu, T.* Rapid lipid-based normalization of membrane protein expression on extracellular vesicles in complex biological samples. Nano Letters. 2019, 19, 11, 7623-7631.
  11. Liu, C., Zhao, Z., Fan, J., Lyon, C. J., Wu, H., Nedelokv, D., Zelazny, A.M., Olivier, K.N., Cazares, L.H., Holland, S.H., Graviss, E. A., Hu, T.* Quantification of Circulating M. tuberculosis Antigens for Rapid Diagnosis and Real-time Treatment Monitoring. Proc. Natl. Acad. Sci. U S A.  2017, 114(15):3969-3974.
  12. Liang K., Liu, F., Fan, J., Sun, D., Bernard, D. W., Li, Y., Yokoi, K., Katz, M. H., Koay, E. J., Zhao, Z., Hu, T.* Nanoplasmonic Quantification of Tumor-derived Extracellular Vesicles in Plasma Microsamples for Diagnosis and Treatment Monitoring. Nature Biomedical Engineering. 2017, 1:0021.




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