Chemo-Proteomic Sr Scientist (BS/MS)

Job Description

Are you a scientist with experience in mammalian cell culture and chemo-proteomic workflows? Come bring your talents to Novartis and grow your career while making a difference to our patients!

The Chemical Biology and Therapeutics department is looking for a highly motivated and versatile candidate for a Senior Scientist I position to support chemo-proteomic and covalent drug discovery efforts by mass spectrometry.

Experience with protein/peptide analysis by mass spectrometry and familiarity with associated protein biochemical techniques (SDS-PAGE, western blotting, immunoprecipitation, tissue culture) is required. Exposure to chemical proteomics and quantitative mass spectrometry workflows (TMT, SILAC, DIA) is highly desired.

The successful candidate will have a demonstrated ability to grow into new fields by adoption of new techniques, and the ability to work independently and accurately on several concurrent projects in a highly dynamic environment. Applicants should have good organizational, team and communication skills, and should be able to critically and objectively interpret results and present findings to stakeholders.

Your responsibilities:

• Mammalian cell culture
• Application of common chemo-proteomic workflows and sample preparation methods including quantitative isotopic labeling strategies (i.e, SILAC, TMT)
• Operation and maintenance of liquid chromatography mass spectrometers and associated equipment in support of discovery programs
• Data reduction and analysis using equipment vendor and 3rd party software
• Preparation of reports summarizing results and interpretations

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you will bring to the role:

Education: B.S. or M.S. equivalent in chemistry, biochemistry, molecular biology, biology or related field, plus minimum of two years relevant experience.
• Hands on experience using liquid chromatography mass spectrometry techniques to identify and quantitate proteins and peptides from complex matrices
• Experience with cell culture as well as standard biochemistry lab techniques and practices
• Additional experience with chemo-proteomic workflows and/or other biophysical characterization techniques is considered a plus
• Demonstrated ability to analyze, interpret, and summarize results independently

Why Novartis?
766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

COVID-19: While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected] .

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network