Principal Scientist - Bioprocess Downstream Purification, Reaction Engineering, High Throughput Scre

Kalamazoo, Michigan
Closing date
Feb 4, 2023

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Physical Sciences, Engineering, Health Sciences, Drug Development
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
What You Will Achieve

The position of Principal Scientist - As part of an interdisciplinary team, will provide scientific leadership, to improve Pfizer's commercial bioprocesses, through the design and delivery of downstream purification, reaction engineering, and high throughput screening technologies. These projects are based on microbial fermentation, biotransformation, and biocatalysis.

How You Will Achieve It
  • Develop and improve bioprocess-based pharmaceutical isolation and purification.
  • Optimize reaction systems employing whole cells, or free / immobilized enzymes.
  • Assist in the scale up of developed processes and provide technical support for commercial biopharmaceutical manufacture.
  • Champion the implementation of new technologies to ensure we deliver or exceed project targets.
  • Work effectively in a fast-paced, team-based laboratory environment.
  • Independently determine and develop experimental programs and participate in setting project objectives.
  • Supervise one or more lab staff to maximize lab productivity.


  • Applicant must have HS Diploma with ten years of relevant experience;
  • OR an Associate's degree with eight years of experience;
  • OR a Bachelor's degree with at least five years of experience;
  • OR a Master's degree with more than three years of experience;
  • OR a Ph.D. with 0-2 years of experience.
  • Experience in related fields preferably in industry-based bioprocess research.
  • Results oriented with a proven track record of accomplishments.
  • Proven innovative and creative problem-solving skills, able to motivate others to exceed goals and deliver results.
  • Ability to design robust experiments and to accurately analyze, interpret, follow-up and communicate experimental data, conclusions, limitations, and recommendations.
  • Must be able to establish productive colleague relationships which foster collaboration and cooperation.
  • Change agile - can effectively cope and excel with change.

Nice to Have
  • Experience in the purification of fermentation / biotransformation derived small molecules.
  • Background or interest in applying Green Chemistry approaches, working with synthetic organic chemists to produce active pharmaceutical ingredients (API).
  • Experience in High Throughput Screening for culture / enzyme selection (i.e. FADS, Microfluidics)

Physical/Mental Requirements

This is a lab-based position: Frequent standing and walking, frequent detailed manual manipulations, and computer-based work.

Non-Standard Work Schedule, Travel or Environment Requirements

First shift position - some overtime and/or weekend work may be required.

Work Location Assignment:On Premise

Other Job Details
  • Last Date to Apply: February 14, 2023
  • Eligible for Relocation Package: YES

Relocation assistance may be available based on business needs and/or eligibility.

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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