The College of Science at the University of Notre Dame seeks a visionary leader to serve as the James C. Parsons and Carrie Ann Quinn Director of the Boler-Parseghian Center for Rare and Neglected Diseases (CRND) (https://crnd.nd.edu/ ). The Director will be appointed as a tenured professor in the Department of Biological Sciences (https://biology.nd.edu/), though the search committee can consider appointments in other departments. The Boler-Parseghian Center for Rare and Neglected Diseases places patients and their families at the core of all their efforts. Members of the center focus on both basic and translational research and work with families affected by rare diseases to combine studies of patient data and tissue with fundamental biological research in order to better understand disease, identify molecular targets, and develop new diagnostics and treatments. In 2022, the College of Science established the rare disease patient advocacy initiative, sponsored by Horizon Therapeutics and Dyne Therapeutics. This program builds on a decade of rare disease outreach and education and a newly established minor in science and patient advocacy. A diverse community of Notre Dame researchers is supported by numerous Centers and Institutes including, the Warren Center for Drug Discovery and Development, Eck Institute for Global Health, the Harper Cancer Research Institute, the Keck Center for Transgene Research. Additional facilities to support research include the AAALAC-accredited Freimann Animal Facility, the Notre Dame Integrated Imaging Facility, and cores in Structural Biology, Bioinformatics, Genomics and Proteomics. Additional information can be found at http://research.nd.edu/core-facilities/.