Postdoctoral Fellow - Cell Biology and Quantitative Microscopy

About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope's translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope's specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation's "Best Hospitals" in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope's commitment to Diversity, Equity and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.

Position Summary

A Postdoctoral Fellow Position is available in the laboratory of Dr. Tijana Jovanovic-Talisman. Biological nanoparticles that are continuously shed by cells - namely extracellular vesicles (EVs) - are an emerging and exciting strategy for performing minimally invasive diagnoses. Because EVs are loaded with disease-specific molecules, they represent an excellent source of biomarkers. The project involves employing cell biology and super-resolution microscopy approaches to characterize extracellular vesicles that contain disease-specific or tissue-specific molecules. Ultimately, the goal is to develop a new platform to perform molecular level diagnoses for precision medicine.

Key Responsibilities include:

We seek a Postdoctoral Fellow with experience in cell biology and quantitative microscopy. The Postdoctoral Fellow will purify and manipulate EVs from cultured cells and plasma, perform imaging experiments using single molecule localization microscopy, and complete data analysis to characterize molecular content of extracellular vesicles.

Basic education, experience and skills required for consideration:

• A Ph.D. degree in Biomedical Sciences, Biophysics, Chemical Engineering, or a related discipline is required with no more than 3 years of postdoctoral training.
• Experience in quantitative microscopy and cell biology.
• Ability to carry out independent research and prepare manuscripts for publication.
• Experience with super-resolution microscopy, extracellular vesicles, and MATLAB programming is preferred.

Additional Information:

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate's experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

About Dr. Jovanovic-Talisman: Tijana Jovanovic-Talisman, PhD is an Associate Professor in the department of Cancer Biology and Molecular Medicine. Dr. Talisman currently has multiple projects actively supported by the NIH. She and team are investigating biological processes that are critical to the progression of cancer and other diseases by using quantitative single molecule localization microscopy.

For more information on the Jovanovic-Talisman Lab, please click here .

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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