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Principal Scientist (Chemical Biology)

Commensurate with education and experience
Closing date
Feb 1, 2023

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Life Sciences, Biophysics, Structural Biology
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
All Industry
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At LifeArc, we want to hear from people who are as passionate as we are about making life science life changing that can improve patients’ lives. 

A bit about the role: 

This role sits within the newly formed Chemical Biology team, leading a cross disciplinary team of protein scientists and medicinal chemists. The successful candidate will demonstrate extensive knowledge across more than one aspect of protein science including structural biology, biophysics, and protein engineering and production, and independently develop and direct specialised non-routine drug discovery experiments. There is also the scope to lead the scientific rationale of one or more projects or lead across multiple projects in a specialised scientific field. Some key accountabilities include: 

  • Ensure projects are robustly planned based on resource allocated and achieves its goals according to project plan 
  • Ensure quality prosecution of project(s) including design of strategy, data summary, interpretation, and reporting 
  • Contribute to budgeting process for project and department as required. 
  • Decide scientific process that will be used on project 
  • Develop and implement novel methodologies as required for project 
  • Direct or participate in research and experiments as appropriate using familiar, new, or novel methodology/techniques 
  • Perform analysis of complex experimental results and develop hypotheses 
  • Propose novel avenues of research to progress the project 
  • Interpret trends and research findings from the external environment for application to team development & progressing/maintaining ‘state of the art’ department capabilities 
  • Advise management and leadership on project strategy and areas of specialist expertise 
  • Contribute to the scientific strategy by advising on projects that would help progress translational challenges 

About you: 
Education & experience required:  

  • Theoretical and practical scientific knowledge and expertise/experience typical of a PhD or equivalent practical work experience in structural biology, biophysics or biochemistry with a track record of impactful contributions 
  • Experience in small molecule, antibody or other therapeutic modality drug discovery (desirable) 
  • Significant scientific project experience 
  • A track record of leading projects or large components of projects that demonstrate the creation of novel solutions to complex problems 
  • Experience coaching and mentoring others 
  • Experience in technical leadership of multidisciplinary projects through to delivery 
  • Experience of line management (desirable) 

Skills & abilities: 

  • Comfortable with ambiguity and resilience in the face of unfavourable outcomes 
  • Strong attention to detail 
  • Intellectual curiosity and ability to apply knowledge/experience to work within areas outside of owns immediate expertise 
  • Critical and analytical thinker, strong problem solver 
  • Organised, Meticulous, Detail orientated and accurate 
  • Excellent communicator - both verbal and written 
  • Ability to influence and persuade others 




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