We are recruiting an experienced and highly motivated Associate Scientist/Biochemist to join the Department of Screening, Profiling & Mechanistic Biology (SPMB) at GSK's Upper Providence research facility in Collegeville, Pennsylvania. The SPMB department is committed to the discovery and mechanistic characterization of high-quality small molecule and biomolecular pre-clinical candidates. The candidate can foresee working in a highly motivating, fast-paced, collaborative and challenging research environment in which delivering a therapeutic solution to patients is the primary focus.
The SPMB department identifies and delivers high quality, biologically relevant pre-clinical leads for GSK therapeutic areas. The candidate will be expected to employ a combination of scientific tools and methodologies in lead discovery, including enzyme activity and binding assay development, ligand-target mechanism of engagement studies, high throughput screening, and compound profiling. The position is for an entry level scientist with a bachelor's degree and 0-2 years of experience. Previous lab-based experience is highly desirable. The Key Skills and Responsibilities of The Associate Scientist Include:
- Development and execution of target relevant, fit for purpose biochemical/enzymatic assays.
- Collaboration with team scientists across the discovery processes from reagent validation, assay development, hit identification, through medium-high throughput screening to support hit identification and optimization of candidate quality molecules.
- Characterization of small molecule and biologic pharmacology using a variety of assay technologies.
- Provide scientific and technical support for multiple project teams across diverse therapeutic areas.
- Ability to work collaboratively in an open lab setting.
- Good laboratory management: document completed lab work and results promptly, clearly, and accurately in electronic notebooks.
Why you? Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:
- B.Sc degree with 0-2 years research laboratory experience in biochemistry, biology, chemistry or a related field is required.
If you have the following characteristics, it would be a plus:
- · Ability to communicate, engage, and build positive relationships with internal research partners.
- Adaptable to changing priorities
- Experience in the design, development, and execution of biochemical assays such as absorbance, fluorescence, FRET, polarization, and mass spectrometry based detection.
- Familiarity with small molecule drug discovery; experience characterizing small molecule inhibitors and/or activators is a plus.
- Experience with Microsoft office suite, such as Excel, PowerPoint
At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader inConsumer Health, strengthening our leadership, and transforming our commercial execution. Now, we're making the biggestchanges we've made to our business in over 20 years.We're on track to separate and create two new companies in 2022:
New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and geneticsscience; and a new world-leading consumer healthcare company of loved and trusted brands.
With new ambition comes new purpose. For New GSK, this is to unite science, talent and technology to get ahead of diseasetogether - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; andas a new GSK where outstanding people thrive.
Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culturethat isambitious for patients
- so we deliver what matters better and faster;accountable for impact
- with clear ownership ofgoals and support to succeed; andwhere we do the right thing
. So, if you're ready to improve the lives of billions, join us at thisexciting moment in our journey. Join our challenge to get Ahead Together.
GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.
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