Postdoctoral Fellow - Molecular Hematology & Therapy

Dr. Michael Andreeff, Section of Molecular Hematology & Therapy, Department of Leukemia at the University of Texas MD Anderson Cancer Center, invites applications for a postdoctoral position. We are looking for a highly motivated and innovative individual with technical expertise in cell, molecular, or cancer biology to conduct a project for mechanism-based combinatorial targeting of drug-resistant leukemia stem cells.

LEARNING OBJECTIVES
The applicant will conduct research into cell death and cell survival pathways and mechanisms of drug resistance in myeloid leukemia stem cells through a combinatorial study of gene mutations, gene expression, protein expression, and responses to drug treatments in leukemia cells. The ultimate goal is to understand the functions of apoptotic regulators, cell signaling pathways, leukemia microenvironmental regulators, and their roles in drug resistance and develop a mechanism-based approach to overcome drug resistance. The researcher will collaborate with established and committed investigators in an interdisciplinary project involving cell culture, flow cytometry, mass cytometry, western blot analysis, immunohistochemistry, RT-PCR, DNA/RNA sequencing, and NSGS/NSG mouse models. The researcher will present scientific results in project meetings, national and international conferences, and high-impact scientific publications.

ELIGIBILITY REQUIREMENTS
The ideal candidate is a recently graduated cell, molecular, or cancer biologist Ph.D. with practical experience and excellent knowledge base in cell death pathways and cell signaling and with expertise in at least one of the following areas of discipline: cell culture, drug treatment, and cell death assay, molecular cloning, flow cytometry, and/or mouse work. Data analysis skill is highly desirable. The applicant enjoys providing practical and theoretical training for students and promotes scientific collaboration within the research group, and will have excellent written and spoken (English) communication skills. The candidate should have one or more publications as a first author.

FACULTY MENTOR
Michael Andreeff, M.D., Ph.D.