Senior Scientist II

Senior Scientist, Cancer Protein Initiative

Department Lineberger Compr Cancer Center-426801 Career Area Research Professionals

Open Until Filled

Position Type Permanent Staff (EHRA NF)

Working Title Senior Scientist, Cancer Protein Initiative

Appointment Type EHRA Non-Faculty Position Number 20048767 Vacancy ID NF0006362 Full Time/Part Time Full-Time Permanent FTE 1

Hours per week 40

Position Location North Carolina, US

Hiring Range Dependent on Qualifications/Experience

Proposed Start Date 12/05/2022

Position Information Primary Purpose of Organizational Unit The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service. OUR VISION Our vision is to be the nation’s leading public school of medicine. We are ranked 2nd in primary care education among all US schools of medicine and 5th among public peers in NIH research funding. Our Allied Health Department is home to five top-ranked divisions, and we are home to 18 top-ranked clinical and basic science departments in NIH research funding. OUR MISSION Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. Patient Care: We will promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond. Education: We will prepare tomorrow’s health care professionals and biomedical researchers by facilitating learning within innovative curricula and team-oriented interprofessional education. We will cultivate outstanding teaching and research faculty, and we will recruit outstanding students and trainees from highly diverse backgrounds to create a socially responsible, highly skilled workforce.

Research: We will develop and support a rich array of outstanding health sciences research programs, centers, and resources. We will provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our University to support outstanding research. We will foster programs in the areas of basic, translational, mechanistic, and population research.

Position Summary The Lineberger Comprehensive Cancer Center (LCCC) seeks to hire a Senior Scientist in the Cancer Protein Initiative. The Senior Scientist will oversee a facility focused on selecting and engineering proteins that can be used to treat and study cancer. They will engage LCCC investigators to identify signaling pathways and biological processes implicated in human malignancies, and lead protein design and selection campaigns aimed at generating novel proteins that can be used to regulate the pathways of interest. The facility will make use of modern methods for selection of protein binders from large engineered libraries and will collaborate with UNC investigators developing new deep learning based methods for protein design. It is anticipated that the engineered proteins will prove useful as both biologic drugs and as targeting ligands for cell-based cancer immunotherapies. UNC is a leader in the development of CAR-T immunotherapies and is regularly advancing new therapeutics into clinical trials. It is expected that the director will publish key findings in leading journals and assist in obtaining extramural funding.

Minimum Education and Experience Requirements Relevant post-Baccalaureate degree required (or foreign degree equivalent); for candidates demonstrating comparable independent research productivity, will accept a relevant Bachelor’s degree (or foreign degree equivalent) and 3 or more years of relevant experience in substitution. May require terminal degree and licensure.

Required Qualifications, Competencies, and Experience Extensive experience in protein engineering, protein production (from mammalian and bacterial cell culture), and biophysical characterization of protein-protein interactions. A strong history of publishing that demonstrates expertise and willingness to disseminate results.

Preferred Qualifications, Competencies, and Experience PhD in a related field. Experience with yeast/phage display or a similar technique is desirable. Special Physical/Mental Requirements Campus Security Authority Responsibilities Not Applicable. Special Instructions Quick Link https://unc.peopleadmin.com/postings/242810 Posting Contact Information Department Contact Name and Title Brianna Anderson, HR Consultant Department Contact Telephone or Email brianna_anderson@med.unc.edu Office of Human Resources Contact Information If you experience any problems accessing the system or have questions about the application process, please contact the Office of Human Resources at (919) 843-2300 or send an email to employment@unc.edu Please note: The Office of Human Resources will not be able to provide specific updates regarding position or application status. Equal Opportunity Employer Statement The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or status as a protected veteran.