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Director, Division of Preclinical Innovation, Chemical Genomics Branch, Stem Cell Translation Labora

NIH/National Center for Advancing Translational Sciences
Rockville, Maryland
Salary is commensurate with experience
Closing date
Dec 1, 2022

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NCATS, a major research component of NIH, is seeking applications from exceptional candidates to direct the Stem Cell Translation Laboratory (SCTL), part of the intramural research program in the Chemical Genomics Branch within the Center’s Division of Preclinical Innovation. The mission of the SCTL — established as an initiative of the Regenerative Medicine Program under the NIH Common Fund — is to address the top methodological or technical hurdles that currently impede therapeutic use of induced pluripotent stem cells and to rapidly deliver the resulting protocols, standards, data, and tool molecules to the public.


Core Responsibilities

The selected candidate will lead the scientific operation of the SCTL, which is comprised of biological scientists and trainees who provide informatics, automation, compound management and project management support. The director will be expected to continue building a world-class collaborative research group that catalyzes new approaches and uses induced pluripotent stem cells (iPSCs) and differentiated cells derived from them; transforming anecdotal reports into replicable, robust protocols; and creating tools and data that facilitate stem cell research and regenerative medicine. High-priority technology research areas for the SCTL include, but are not limited to, derivation of a detailed set of QC standards to assess the differentiation state at specific stages leading to mature differentiated cell types of desired lineages; development of methods to assess heterogeneity of cultures and the functional role of this heterogeneity during directed differentiation; development of methods to produce mature differentiated cells with high efficiency, with the likely requirement for development of 3-D culture conditions; and further advancement of modern gene-editing technologies in the context of iPSCs. The SCTL will collaborate with researchers to validate the methods developed for suitability in regenerative medicine applications. The ideal candidate should be highly innovative, interactive and collaborative. The selected candidate also should possess strong oral and written communication skills, as he or she will serve as a spokesperson for the SCTL at national and international forums.



The successful candidate will hold a doctoral degree in a relevant field and be a recognized expert and accomplished leader in the field of stem cell biology. He or she must have a strong track record in generating and working with iPSCs, embryonic stem cells, and/or adult stem cells, investigating their biology, differentiation to distinct cell types, screening using small molecules or other modalities, and potential iPSC therapeutic applications.



Salary is commensurate with experience and accomplishments; a full civil service benefits package — including retirement; health, life and long-term care insurance; Thrift Savings Plan (401K equivalent) participation, etc. — is available.


How to Apply

Please submit a cover letter describing your interest in the position, including a vision statement for directing the SCTL, a current curriculum vitae and complete bibliography, and the names of and contact information for up to five references to


Review of applications will begin immediately and will continue until the position is filled.


Additional Information

Employment is subject to the successful completion of the pre-appointment process (i.e., background investigation, verification of qualifications and job requirements, completion of onboarding forms, submission of required documents, etc.).


At the discretion of the supervisor and NIH policy, you may be eligible for workplace flexibilities, which may include remote work or telework options and/or flexible work scheduling. These flexibilities may be requested in accordance with the NIH Workplace Flexibilities policy.

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