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Associate Scientist, Upstream Process Development

King of Prussia, Pennsylvania
Closing date
Oct 8, 2022

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Are you seeking an opportunity as a cell line or cell culture scientist with ability to advance the cell line development, cell culture process platforms and handle large sets of complex data? If so, this Associate Scientist role could be an ideal opportunity to explore.

As an Associate Scientist within Biopharm DS Process Development, you will have the opportunity to develop new methods and build more capability in our platform technologies or support project progression. The team will have access to the latest technologies in cell line engineering, bioreactor operations, and analytical instruments. Our aim is to integrate innovative expression and process platforms, automation and advanced data analytics into the upstream process development workflow.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

  • Supporting the cell lines for mid- and late-phase projects, further development and optimization when needed, such as host/vector engineering or medium development to improve product yield and quality.
  • Supporting authoring and/or verification of cell line development sections in the regulatory submissions.
  • Execution of small-scale bioreactor studies for cell line characterization, process fit, and process development.
  • Interacting with colleagues in key partner groups: scientists/engineers responsible for project upstream process development, downstream process development and analytical method development scientists, data scientists and statisticians.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • Bachelor's in Biology/Biochemical/Biochemical Engineering or related Biological Sciences with 2+ years of industrial experience OR Master's degree in Biology/Biochemical/Biochemical Engineering or related Biological Sciences
  • Knowledge in recombinant DNA and mammalian cell culture technologies.
  • Experience working in a biological laboratory and familiarity with sterile technique and other general laboratory procedures.

Preferred Qualifications:
  • Hands-on experience with mammalian recombinant cell line development, such as performing transfection, single cell subcloning and clone selection.
  • Knowledge on CRISPR gene knock-out.
  • Ability to generate scientific hypothesis, conceptualize and execute meaningful study designs, draw and present conclusions.
  • Operation of automated small-scale bioreactors and/or bench-top reactors.
  • Writing and reviewing technical documents with a basic understanding of regulatory requirements from cell line-perspective.
  • Experience with statistical data analysis
  • Scientific knowledge of genetics, cellular metabolism and physiology.
  • Excellent verbal and written communication skills
  • Ability to work in matrix team environment

Why GSK?

Uniting science, talent, and technology to get ahead of disease together

At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader in Consumer Healthcare, strengthening our leadership, and transforming our commercial execution. Now, we're making the most significant changes we've made to our business in over 20 years. We're on track to separate and create two new companies in 2022: New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and genetics science; and a new world-leading consumer healthcare company of loved and trusted brands.

With new ambition comes new purpose. For New GSK, this is to unite science, talent, and technology to get ahead of disease together - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; and as a new GSK where outstanding people thrive.

Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culture that is   ambitious for patients  - so we deliver what matters better and faster;   accountable for impact  - with clear ownership of goals and support to succeed; and where we do the right thing . So, if you're ready to improve the lives of billions, join us at this exciting moment in our journey. Join our challenge to get Ahead Together.




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