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Associate Director, Biostatistics (Nonclinical)

Cambridge, Massachusetts
Closing date
Oct 9, 2022

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Life Sciences, Computational Biology
Position Type
Full Time
Job Type
Organization Type
All Industry, Pharma
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Pfizer's ECD Statistics is looking for a motivated and experienced statistician with a solid background in nonclinical statistics, strong consulting skills, and an interest in collaborating with research scientists in drug discovery and development. The candidate will work closely with research scientists seeking to discover new medicines in a variety of therapeutic areas by supporting the design and analysis of preclinical experiments, covering all aspects of drug discovery from disease target identification, pharmacology studies, animal model development, biomarker development and demonstration of proof-of-concept. The focus will be on both "platform" approaches (i.e., ensuring robust assay methods) as well as specific project approaches. The ideal candidate will have a genuine interest in understanding drug target biology to provide effective statistical consultation with biological scientists.

  • Collaborate with preclinical scientists across research units (Immunology & Inflammation, Internal Medicine, Rare Disease, CTI) to design, analyze, and present experiments.
  • Bring innovative statistical thinking and methods to help drive the enhanced quantitative drug discovery and development paradigm within Pfizer.
  • Ensure rigorous approaches are taken to ensure good scientific practices are followed: excellent statistical methods utilized and documented in protocols, analysis plans and manuscripts, and assay methods are appropriately blinded, randomized and designed.
  • Serve as a core member of scientific teams responsible for determining strategy and delivering results in a timely and high-quality manner.
  • Work with scientists to understand the biology and improve existing biomarkers, endpoints, derive new endpoints, and develop "fit-for-purpose" statistical models.
  • Use statistical expertise to prepare both internal and external reports, presentations, and manuscripts, with the aim to improve the quality of internal decision making and increase our influence in the external environment.
  • Where possible, standardize processes and methodologies within and possibly across therapeutic areas, may include developing statistical tools to aid scientists in standardizing analyses.
  • Provide statistical expertise on regulatory submissions and ensure quality of deliverables.

  • PhD in Statistics/Biostatistics and at least 3-5 years of pharmaceutical experience or a MS in Statistics/Biostatistics and at least 5-8 years of pharmaceutical experience.
  • Strong preclinical and non-clinical statistics experience is required.
  • Must have strong technical competence.
  • Capability to provide statistical leadership to cross-functional teams.
  • Sound understanding of design of experiments, assay development, and statistical applications for preclinical research.
  • Interest in biology, graduate level training preferred.
  • Good knowledge of drug development regulations pertinent to statistical analysis

  • Preferred candidates will have good computational skills in SAS, R, or S-Plus.
  • Strong communication skills and the ability to work collaboratively with research scientists are essential.
  • Demonstrated ability to work effectively as a part of a team.

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.


ability to perform mathematical calculations and ability to perform complex data analysis

Relocation support available
Work Location Assignment:Flexible



Relocation assistance may be available based on business needs and/or eligibility.


Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

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