Computational Genomic Scientist (75602)

“Fantastic opportunity for your talents in human resources to shine at a world-class, health-care organization”

Computational Genomic Scientist (75602)

Weill Cornell Medicine is committed to excellence in patient care, scientific discovery and the education of future physicians in New York City and around the world. Since 1898, our doctors and scientists have been engaged in world-class clinical care and cutting-edge research that connect patients to the latest treatment innovations and prevention strategies.

Position Summary

Performs in-depth analyses of high-throughput data (single-cell and bulk RNA-seq, CITE-seq, ATAC-seq, ChIPseq/CUT&TAG, WGBS, etc) to address a multitude of biological or clinical questions at the forefront of cutting-edge biomedical research at Weill Cornell Medicine (WCM), spanning basic and biomedical science.

Job Responsibilities

• Responsible for designing and carrying out bioinformatics and biostatistical analyses of next generation sequencing (NGS) datasets from a variety of platforms, including Illumina and 10X Genomics.
• Provides a strong focus on quality control and critical assessment of experimental design as well as normalization, clustering, visualization, cellular annotation (for single-cell assays) and additional downstream analyses.
• Collaborates with cross-disciplinary teams from a variety of labs and centers; advises on experimental design, data handling and analysis practices for a variety of experimental approaches, including transcriptomics, genomics and epigenomics methods.
• Critically reviews, analyzes, summarizes, and communicates results and limitations of analyses to research faculty, staff, and clinical collaborators.
• Prepares results for publications, works with collaborators for writing manuscripts and optimizing visualizations.
• Writes robust code that is rigorously documented and liberally commented that that can easily be shared via code repositories.
• Organizes data in a systematic, resource-conscious way. Curates metadata and uploads data sets to public repositories.
• Actively participates in identifying, evaluating, and benchmarking new computational tools and methodologies that will meet the scientific goals of constituents.
• Educates faculty and lab members in contemporary bioinformatics methods and best practices via small group training and one-on-one consulting.

Education

• Master's Degree in related field.

Experience

• Master’s degree or PhD (preferred) in Statistical/Computational Genomics or Bioinformatics, with a strong background in the biological sciences.
• Expertise in Unix environment, shell scripting, high performance computing, cloud and cluster environments, and version control with git.
• Intimate knowledge of common high-throughput sequencing analysis tools such as short read/sequence aligners (STAR, salmon, BWA), single-cell analysis packages (Bioconductor, scanpy, Seurat), visualization approaches, and functional annotation of sequencing data.

Knowledge, Skills and Abilities

• Strong programming skills in at least one of Python, R, Julia; or compiled languages such as C/C++, Rust, and JAVA.
• Deep knowledge of genomics, cell biology, and experimental protocols related to DNA sequencing.
• Advanced critical thinking skills.
• Ability to analyze problems and provide creative solutions
• Detail oriented and accurate with strong analytical, research, evaluation, and writing skills.
• Ability to communicate in both scientific written reports and professional presentations.

https://career4.successfactors.com/sfcareer/jobreqcareerpvt?jobId=75602&company=C0000274692P&st=5860FCC12C37058A8EBCE361CDCEE97FD1C22F97

Weill Cornell Medicine is a comprehensive academic medical center that's committed to excellence in patient care, scientific discovery, and the education of future physicians in New York City and around the world. Our doctors and scientists-faculty from Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences, and the Weill Cornell Physician Organization-are engaged in world-class clinical care and cutting-edge research that connect patients to the latest treatment innovations and prevention strategies. Located in the heart of the Upper East Side's scientific corridor, Weill Cornell Medicine's powerful network of collaborators extends to its parent university Cornell University; to Qatar, where an international campus offers a U.S. medical degree; and to programs in Tanzania, Haiti, Brazil, Austria and Turkey. Our medical practices serve communities throughout New York City, and our faculty provide comprehensive care at New York-Presbyterian Hospital/Weill Cornell Medical Center, New York-Presbyterian/Lower Manhattan Hospital, and New York-Presbyterian/Queens. At Weill Cornell Medicine, we work together to treat each individual, not just their conditions or illnesses, as we strive to deliver the finest possible care for our patients - the center of everything we do. Weill Cornell Medicine is an Equal Employment Opportunity Employer. Weill Cornell Medicine provides equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information.