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Senior Scientist, Translational Research

Boulder, Colorado
Closing date
Oct 5, 2022
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Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

The Cell Biology and Translational Research Group at the Pfizer-Boulder RU develops and performs cell-based assays to support oncology drug development. The group is seeking to add a key team member with a strong track record and background in cancer biology and basic mechanisms of targeted cancer therapeutics. The successful candidate will have an in-depth working knowledge of cancer genomics and cancer-associated signaling pathways. Broad technical skills in cellular and molecular biology are required. The new team member will work on a diverse array of projects to expand and enhance the product portfolio. Projects will include new therapeutic target discovery and validation, development of cell-based assays to interrogate mechanisms of drug action and elucidation of novel drug resistance mechanisms.

The new team member will be part of a dynamic and multi-disciplinary group. Extensive opportunities are available for cross-functional collaborations with other groups, including in vivo pharmacology, proteomics, bioinformatics and structural biology.

How You Will Achieve It

  • Work independently to develop and plan projects
  • Implement and successfully complete experiments to support drug development programs
  • Collaborate with team members and cross-functional groups to successfully accomplish project goals
  • Provide deliverables to the team according to project deadlines
  • Contribute to team building and foster a collegial work environment
  • Generate high-quality written reports and oral presentations to disseminate results to the key stakeholders


  • PhD in molecular biology, biochemistry, pharmacology or related science plus minimum 3 years of postdoctoral wet-lab research experience either in industry or academia
  • Proven track record in cancer biology, oncology and pharmacology
  • Knowledge and successful technical application of molecular biology, cell biology, pharmacology, genomics, and proteomics laboratory methods to advance oncology drug discovery, drug characterization and biomarker discovery
  • Expertise in the following molecular and cell biology methods: CRISPR/cas9-based gene editing, molecular cloning, RNAseq and whole exome seq, proteomics
  • High-level oral and written communication skills
  • Ability to work in a fast-paced environment

  • Proficiency in computational data analysis methods

  • Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis

  • Able to adhere to safe work practices and perform lab work with appropriate personal protection equipment such as but not limited to safety goggles, facial mask, gloves, lab coat/ protective gowning, and closed toe shoes
  • Able to work at flexible hours occasionally when performing time-sensitive experiments

  • Eligible for relocation assistance
  • Work Location Assignment:On Premise. On Premise colleagues work in a Pfizer site because it's needed to get their job done. They may have flexibility to work remotely from time to time, but they are primarily on-site


Relocation assistance may be available based on business needs and/or eligibility.

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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