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Chemical Biologist - Investigator

Collegeville, Pennsylvania
Closing date
Sep 30, 2022

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Do you have a profound interest to solve hard biological problems? If so, this role of Investigator would be a great opportunity to consider.

As an Investigator within the Chemical Biology group, you will be carrying out experimental work to support initiation and progression of GSK programs and capabilities. You will be influencing the experimental strategies of the team and contributing to establishing a culture and environ

Values and Expectations:
  • Collaborative working with data scientists, biochemists, chemoproteomics scientists and cell biologists.
  • Supervising and developing other scientists
  • Work through problems logically and apply innovative solutions (appropriate to grade)
  • Adopt new technologies and apply them to project work
  • Use scientific literature and database resources in the execution of project related work
  • Exhibit flexibility, being open to new ways of working

Key responsibilities may include:

  • Maintaining high individual lab-based chemical biology productivity.
  • Enable the team by driving the design and implementation of experiments to solve biological questions.
  • Help GSK establish industry-leading, cutting-edge chemical biology capabilities
  • Establish personal and profession development goals and outline plan to meet them.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • BS degree with 10 years experience or MS with 5 years experience in chemical biology, or related field
  • Publications on contemporary chemical biology techniques and literature.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

  • Preferred qualifications:

  • Ph.D. in chemical biology, or related field
  • Synthetic chemistry -Develop chemical probes and tool compounds to mine complex pathways and enable mechanistic studies and characterization of novel chemical matter
  • Able to effectively work and communicate across the chemistry/biology interface.
  • Eagerness to grow and develop as a scientist.
  • Familiarity with array chemistry and accompanying instrumentation
  • Expertise in mass spectrometry-based proteomics, including proteome profiling, PTM, protein-protein interaction, chemoproteomics, etc
  • Demonstrated track record of peer reviewed publications and scientific meeting presentations based predominantly on their own work
  • Techniques related to target identification, validation, tractability, and engagement- including but not limited to protein degradation, ligand directed chemistry, imaging probes, affinity-based platforms
  • Design and execute clear strategies towards chemical biology tool molecule synthesis, including alkyne, biotinylated, and photoaffinity probes

Why GSK?

At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader inConsumer Health, strengthening our leadership, and transforming our commercial execution. Now, we're making the biggestchanges we've made to our business in over 20 years.We're on track to separate and create two new companies in 2022:New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and geneticsscience; and a new world-leading consumer healthcare company of loved and trusted brands. ​

With new ambition comes new purpose. For New GSK, this is to unite science, talent and technology to get ahead of diseasetogether - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; andas a new GSK where outstanding people thrive. ​

Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culturethat isambitious for patients- so we deliver what matters better and faster;accountable for impact- with clear ownership ofgoals and support to succeed; andwhere we do the right thing. So, if you're ready to improve the lives of billions, join us at thisexciting moment in our journey. Join our challenge to get Ahead Together. ​


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