Post-Doc Research Associate: Lipid Nanoparticle (LNP) formulations with adjuvants

Employer
GSK
Location
Rockville, Maryland; Boston, Massachusetts; Raleigh, North Carolina; Cleveland, Ohio; Nashville, Tennessee; Austin, Texas; Dallas, Texas; Houston, Texas
Salary
Competitive
Closing date
Oct 5, 2022

View more

Discipline
Physical Sciences, Chemistry
Job Type
Postdoc, Research Scientist
Organization Type
Pharma
Location: Rockville, MD - onsite

Are you energized by the challenge of shaping and accelerating the scientific expertise of a vaccine lipid nanoparticle formulations and adjuvants program? If so, this Post-Doc Research Associate opportunity could be an exciting opportunity to consider.

Job Purpose

As a “Post-Doc Research Associate: Development of novel Lipid Nanoparticle (LNP) formulations with adjuvants for mRNA and protein vaccines” you will lead development of novel Lipid Nanoparticle (LNP) formulations with adjuvants to induce potent and durable adaptive immunity from mRNA and protein vaccines.

Details ( Your Responsibilities ):

This role will provide YOU the opportunity to lead key activities to progress YOUR career.

The successful candidate will be a self-starter and contribute towards GSK's efforts to develop new formulation and delivery strategies to enhance the safety, efficacy and longevity of its mRNA and subunit protein vaccine platforms. The role would allow the candidate to lead a highly multidisciplinary project in a matrix team environment involving immunology, formulation sciences and adjuvants teams and use cutting-edge technologies and state-of-the-art instruments and laboratories at GSK to advance the RNA and protein vaccine field. This will be a highly collaborative project between various GSK teams for developing and physico-chemical characterization of new LNP and adjuvant formulations using DOE approach and deep characterization of vaccine potency and immune responses in vitro and in vivo.

This role will be primarily located at GSK (Rockville, Maryland, US).

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

Ph.D. in Chemistry, Biochemistry, Chemical engineering, Bioengineering/Biomedical Engineering, Pharmaceutical Sciences, Biotechnology, Immunology, Biology or a related scientific field with research experience
  • Laboratory hands-on experience with demonstrated success in RNA-Lipid Nanoparticle (LNP) and protein adjuvant formulations.
  • Laboratory hands-on experience in making formulations containing RNA, LNP, adjuvants, small molecule immunomodulators and protein antigens using NanoAssemblr, Microfluidic devices & other technologies and performing analytical techniques like HPLC/UPLC, DLS, CD, zeta potential, UV-Vis and fluorescence spectrophotometry and RNA-related analytics like Ribogreen assays, gel electrophoresis, capillary electrophoresis, etc.
  • Experience with innate sensing and immunological testing of vaccine formulations in mice models.


Preferred Qualifications:

If you have the following characteristics, it would be a plus:
  • Experience in/understanding of immunology especially mechanisms of innate and adaptive immunity of vaccines and formulations and/or molecular biology.
  • Detail oriented with strong analytical and problem-solving skills.
  • Good interpersonal and communication skills and a team player in a cross-functional collaborative environment.
  • Experience in discovery and/or early development of biopharmaceuticals.
  • Good understanding of biopharma / vaccine development process.
  • Proficiency in written and spoken English.


To be successful in the role, this person would need the ability to understand, interpret, and communicate complex scientific data; must be comfortable conversing with opinion leaders regarding highly technical information; must be a self-starter able to handle multiple projects concurrently; possess a good balance of creative, analytical and strong communication skills; ability to be productive and successful in an intense work environment and he/she must be a Team Player.

Why GSK?

At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader inConsumer Health, strengthening our leadership, and transforming our commercial execution. Now, we're making the biggestchanges we've made to our business in over 20 years.We're on track to separate and create two new companies in 2022:New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and geneticsscience; and a new world-leading consumer healthcare company of loved and trusted brands.​



With new ambition comes new purpose. For New GSK, this is to unite science, talent and technology to get ahead of diseasetogether - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; andas a new GSK where outstanding people thrive.​



Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culturethat isambitious for patients- so we deliver what matters better and faster;accountable for impact- with clear ownership ofgoals and support to succeed; andwhere we do the right thing. So, if you're ready to improve the lives of billions, join us at thisexciting moment in our journey. Join our challenge to get Ahead Together.​

*LI-GSK

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve.

GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.

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